Results 41 to 50 of about 559,127 (246)

Impact of variation in voluntary moderate deep inspiration breath hold on the 3D dose distribution in breast cancer radiotherapy

Technical Innovations & Patient Support in Radiation Oncology
Aim: Determination of impact of variations during voluntary moderately deep inspiration breath hold (vmDIBH) on doses to organs at risk (OAR) and target coverage in patients undergoing radiotherapy (RT) for left-sided breast cancer (BC).
Lotte van der Werf, Lars Murrer, Karolien Verhoeven, Debby Knarren, Kirsten Kremer, Femke Vaassen, Liesbeth Boersma, Michel Öllers   +7 more
doaj   +1 more source

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Interobserver variability in organ at risk delineation in head and neck cancer

Radiation Oncology, 2021
Background In radiotherapy inaccuracy in organ at risk (OAR) delineation can impact treatment plan optimisation and treatment plan evaluation. Brouwer et al.
J. van der Veen, A. Gulyban, S. Willems, F. Maes, S. Nuyts   +4 more
doaj   +1 more source

Evaluation of Image Registration Accuracy for Tumor and Organs at Risk in the Thorax for Compliance With TG 132 Recommendations [PDF]

, 2018
Purpose To evaluate accuracy for 2 deformable image registration methods (in-house B-spline and MIM freeform) using image pairs exhibiting changes in patient orientation and lung volume and to assess the appropriateness of registration accuracy ...
Che, Shaomin, Guy, Christopher L., Jan, Nuzhat, Rosu-Bubulac, Mihaela, Weiss, Elisabeth, Zhao, Sherry   +5 more
core   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Magnetic resonance imaging thoracic organ-at-risk atlas for radiation oncology

Physics and Imaging in Radiation Oncology
Background and purpose: The use of Magnetic Resonance imaging (MRI) for radiotherapy (RT) planning for locally advanced non-small cell lung cancer (LA NSCLC) could improve RT precision due to its superior soft tissue definition compared to computed ...
Hannah Bainbridge, Michael J. Dubec, Andreas Wetscherek, Rob H.N. Tijssen, Jose Belderbos, Corine Van Es, David Cobben, Guido H.W. van Bogerijen, David Woolf, Marcel van Herk, Ferry Lalezari, Dow-Mu Koh, Fiona McDonald, Corrine Faivre-Finn   +13 more
doaj   +1 more source

Evaluation of Testis as Organ at Risk in Carcinoma Rectum with Various Radiotherapy Delivery Techniques [PDF]

Middle East Journal of Cancer
Background: Due to the close approximation of testis to radiotherapy treatment field in male carcinoma rectum patients, it receives either scattered or direct radiation.
Poornachandra Tejaswi Siddappa, Shamsundar Sunkappa, Vinay Desai, Jagannath Kunigal Puttaswamy, Nanda Ramanand, Aradhana Katke, Thejaswini Boraiah   +6 more
doaj   +1 more source

Converting Treatment Plans From Helical Tomotherapy to L-Shape Linac: Clinical Workflow and Dosimetric Evaluation. [PDF]

, 2018
This work evaluated a commercial fallback planning workflow designed to provide cross-platform treatment planning and delivery. A total of 27 helical tomotherapy intensity-modulated radiotherapy plans covering 4 anatomical sites were selected, including ...
Benedict, Stanley H, Fragoso, Ruben C, Nair, Chithra Kumaran, Qiu, Jianfeng, Rao, Shyam, Rong, Yi, Valicenti, Richard K, Wright, Cari, Yuan, Zilong   +8 more
core   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

NRG Oncology-Radiation Therapy Oncology Group Study 1014: 1-Year Toxicity Report From a Phase 2 Study of Repeat Breast-Preserving Surgery and 3-Dimensional Conformal Partial-Breast Reirradiation for In-Breast Recurrence. [PDF]

, 2017
PURPOSE: To determine the associated toxicity, tolerance, and safety of partial-breast reirradiation. METHODS AND MATERIALS: Eligibility criteria included in-breast recurrence occurring \u3e1 year after whole-breast irradiation, \u3c3 \u3ecm, unifocal ...
Arthur, Douglas W., Brown, Doris R., Canaday, Daniel J., Cohen, Randi J., Currey, Adam D., Cuttino, Laurie W., Fisher, Christine M., Haffty, Bruce G., Hayes, Shelly B., Jagsi, Reshma, Kuerer, Henry M., McCormick, Beryl, Sahijdak, Walter M., Simone, Nicole L., Todor, Dorin A., White, Julia, Winter, Kathryn A., Woodward, Wendy A.   +17 more
core   +1 more source