Results 61 to 70 of about 559,127 (246)

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song, Jonathan Baron, Carlos Chavez Perez, Sidharth Ramesh, Jane Minturn, Kavita A. Desai, Amish C. Shah, Jean M. Belasco, Kristina A. Cole, Michael J. Fisher, Phillip B. Storm, Peter M. Madsen, Goldie Kurtz, Robert A. Lustig, Christine Hill‐Kayser, Michael J. LaRiviere   +15 more
wiley   +1 more source

Role of MRI-Based Functional Imaging in Improving the Therapeutic Index of Radiotherapy in Cancer Treatment

Frontiers in Oncology, 2021
Advances in radiation technology, such as intensity-modulated radiation therapy (IMRT), have largely enabled a biological dose escalation of the target volume (TV) and reduce the dose to adjacent tissues or organs at risk (OARs).
Mei Li, Mei Li, Qin Zhang, Kaixuan Yang
doaj   +1 more source

Result Analysis of Treatment Planning System Between 3-Dimensional Conformal Radiation Therapy Technique and Intensity Modulated Radiation Therapy Technique in Nasopharyngeal Cancer Cases [PDF]

, 2017
This study aims to analyze the difference in results between TPS 3D-CRT radiotherapy irradiation technique and IMRT radiotherapy irradiation technique in nasopharyngeal cancer cases based on the doses received by the target volume and organs at risk and ...
Apriantoro, N. H. (Nursama), Irsal, M. (Muhammad), Kasih, P. C. (Prima), Wibowo, B. S. (Bambang)   +3 more
core  

Measurement of secondary particle production induced by particle therapy ion beams impinging on a PMMA target [PDF]

, 2016
Particle therapy is a technique that uses accelerated charged ions for cancer treatment and combines a high irradiation precision with a high biological effectiveness in killing tumor cells [1].
Battistoni, G., Bellini, F., Collamati, F., De Lucia, E., Durante, M., Faccini, R., Frallicciardi, P. M., Marafini, M., Mattei, I., Morganti, S., Muraro, S., Paramatti, R., Patera, V., Piersanti, L., Pinci, D., Rucinski, A., Russomando, A., Sarti, A., Sciubba, A., Senzacqua, M., Solfaroli Camillocci, E., Toppi, M., Traini, G., Voena, C.   +23 more
core   +1 more source

The Role of Invasive Procedures in the Treatment of Complicated Gastrointestinal Graft‐Versus‐Host Disease in Pediatric Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Gastrointestinal graft‐versus‐host disease (GI GVHD) following hematopoietic stem cell transplant is typically managed with medical therapy, but surgery and angioembolization may be warranted in selected cases with life‐threatening complications.
Gaia Brunetti, Giorgio Persano, Chiara Grimaldi, Pier Luigi Di Paolo, Carmen Malaspina, Francesco Quagliarella, Valerio Balassone, Anna Chiara Iolanda Contini, Gian Luigi Natali, Rita Alaggio, Ivan Pietro Aloi, Tamara Caldaro, Alessandro Crocoli   +12 more
wiley   +1 more source

Support Vector Machine Model Predicts Dose for Organs at Risk in High-Dose Rate Brachytherapy of Cervical Cancer

Frontiers in Oncology, 2021
IntroductionThis study aimed to establish a support vector machine (SVM) model to predict the dose for organs at risk (OARs) in intracavitary brachytherapy planning for cervical cancer with tandem and ovoid treatments.MethodsFifty patients with loco ...
Ping Zhou, Xiaojie Li, Hao Zhou, Xiao Fu, Bo Liu, Yu Zhang, Sheng Lin, Haowen Pang   +7 more
doaj   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Uncertainty in multitask learning: joint representations for probabilistic MR-only radiotherapy planning

, 2018
Multi-task neural network architectures provide a mechanism that jointly integrates information from distinct sources. It is ideal in the context of MR-only radiotherapy planning as it can jointly regress a synthetic CT (synCT) scan and segment organs-at-
Alexander, Daniel C., Bragman, Felix J. S., Cardoso, M. Jorge, Eaton-Rosen, Zach, Hawkes, David J., Li, Wenqi, McClelland, Jamie R., Ourselin, Sebastien, Tanno, Ryutaro   +8 more
core   +1 more source

Characteristics of non-coplanar IMRT in the presence of target-embedded organs at risk [PDF]

, 2015
Background The aim is to analyze characteristics and to study the potentials of non-coplanar intensity modulated radiation therapy (IMRT) techniques. The planning study applies to generalized organ at risk (OAR) – planning target volume (PTV) geometries.
Bratengeier, Klaus, Holubyev, Kostyantyn
core   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source