Results 91 to 100 of about 613,865 (306)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Black Sea Tourism and the Orient: Bulgarian Visual Images (1920s–1980s)
The article examines the image, interpretations and transformations of the Orient, spread in the Bulgarian cultural space in the 1920s and in the 1960s–1980s.
Georgeta Nazarska
doaj +1 more source
ORIENT LIGHT? THE IMAGE OF JAPAN IN AMERICAN POPULAR CINEMA OF THE LAST DECADE
The paper Orient Light? The Image of Japan in American popular cinema of the last decade focuses on the stereotypes about Japan featured in American films.
Karolina Robaczek
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Citizenship after orientalism: Ottoman citizenship [PDF]
About the book: A keen analysis of the social, political and economic determinants of Turkish politics with an exploration of the different dimensions of the republican model of Turkish citizenship, providing the reader with a comprehensive account of ...
Isin, Engin F.
core
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
The determinants of scientific research agenda: Why do academic inventors choose to perform patentable versus non-patentable research? [PDF]
This paper explores the determinants of scientific research agenda. By using an original dataset that includes extensive information about 269 French academic inventors, we analyze why scientists choose to perform patentable versus non-patentable ...
Hussler Caroline, Pénin Julien
core
Caracterização das explorações de pequenos ruminantes da região da Beira Serra [PDF]
Dissertação de Mestrado em Tecnologias da Produção AnimalEste trabalho teve como objetivo o estudo das explorações de pequenos ruminantes, através de uma análise do sistema de exploração.
Carvalho, Maria Madalena Lemos +2 more
core
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Brightest Cluster Galaxy Alignments in Merging Clusters
The orientations of brightest cluster galaxies (BCGs) and their host clusters tend to be aligned, but the mechanism driving this is not clear. To probe the role of cluster mergers in this process, we quantify alignments of 38 BCGs in 22 clusters ...
Foote, Drake +2 more
core +1 more source

