Results 111 to 120 of about 76,095 (267)

Genomic biomarkers of immunotherapy plus chemotherapy in patients with advanced NSCLC: Insights from the phase 3 ORIENT-11 study. [PDF]

iScience
Liao J, Huang J, Chen X, Hong S, Chen G, Zhang Y, Zhou T, Zhuang W, Pang L, Yang Y, Zhang L, Fang W.   +11 more
europepmc   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Things are looking (farther) up: Upward gaze orientation is overestimated. [PDF]

Atten Percept Psychophys
Shaffer DM, Juarez M, Shaver A, Brown C, Hill B, Shaffer RE.   +5 more
europepmc   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The grammar of the gallery: room corners influence the mental representation of picture arrangements. [PDF]

Front Psychol
Garsoffky B, Benkert M, Schwan S.
europepmc   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Soft Tissue Coverage Options Following Total Hip Arthroplasty: What to Do When a Wound Breaks Down. [PDF]

Arthroplast Today
Harper KD, Maiorino E.
europepmc   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Voci sospese e contese. La dispersione delle polarità orientaliste nei limbi sonori extra-extradiegetici

Cinergie, 2013
Marco Dalla Gassa
doaj   +1 more source

Courtship choreography is stabilized among genetically isolated populations. [PDF]

Behav Ecol
Butterworth NJ, White TE, Dawson BM, Appleton J, McDonald C, McGaughran A, Markowsky G, Bayless KM.   +7 more
europepmc   +1 more source