Results 131 to 140 of about 76,095 (267)

CapeOX (capecitabine and oxaliplatin) combined with sintilimab and bevacizumab biosimilar (IBI305) for first-line treatment of advanced gastric or oesophagogastric junction adenocarcinoma: study protocol for a single-arm, phase Ib/II trial. [PDF]

BMJ Open
Dai R, Zhang P, Cheng M, Bi F, Zhou J, Liu M.   +5 more
europepmc   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Boron symbiotaxis: a new concept in host-microbiome communication. [PDF]

Front Microbiol
Pîrvu AS, Biţă A, Scorei IR, Gheonea DI, Mogoşanu GD.   +4 more
europepmc   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Breaking Down the Posteromedial Corner: Medial Collateral Ligament Augmentation. [PDF]

Video J Sports Med
Gerhold C, Koluman AC, Vega J, Gómez Verdejo F, LaPrade R, Chahla J.   +5 more
europepmc   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Pericolo Giallo. “Musi gialli” nel mirino della letteratura e cinematografia angloamericana

Cinergie, 2013
Cristina Colet
doaj   +1 more source

El relato de viaje de José María Guzmán por Oriente (1837): Entre construcción identitaria y palabra panfletaria

Cuadernos del CILHA
Con base en un postulado sociocrítico que sostiene que el objeto cultural es una producción socio-histórica, me propongo examinar la noción de revelación en un relato de viaje mexicano que data de la primera mitad del siglo XIX.
Assia Mohssine
doaj  

Cost-effectiveness analysis of Cadonilimab in first-line treatment of advanced HER2-negative gastric cancer or gastroesophageal junction cancer. [PDF]

Ther Adv Gastroenterol
Zhu K, Qin M, Pan Z, Huang J.
europepmc   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source