Results 141 to 150 of about 343,705 (317)

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Does chemotherapy regimen matter for first-line immunochemotherapy in low PD-L1-expressing esophageal squamous cell carcinoma? A systemic review and meta-analysis. [PDF]

Esophagus
Guo JC, Lin PS, Shau WY, Shao YY, Kuo HY, Chen CL, Hsu CH.   +6 more
europepmc   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Pericolo Giallo. “Musi gialli” nel mirino della letteratura e cinematografia angloamericana

Cinergie, 2013
Cristina Colet
doaj   +1 more source

Predicting Immunotherapy Outcomes in NSCLC Using RNA and Pathology from Multicenter Clinical Trials. [PDF]

Adv Sci (Weinh)
Wang Z, Fang Y, Huang X, Ma G, Mao Q, Lu X, Rong G, Yu Y, Wang Y, Huang Z, Sun H, Wu J, Gu W, Huang N, Wu J, Zhou R, Rong X, Zheng S, Li S, Wang G, Wang L, Qiu W, Jiang L, Luo P, Liu Y, Bin J, Liao Y, Shi M, Wu Z, Wang J, Liao W, Chen G, Zeng D.   +32 more
europepmc   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Apologia dell’oppio. Lo stereotipo della fumeria tra fascinazione e razzismo

Cinergie, 2013
Corrado Neri
doaj   +1 more source

Wayfinding with Impaired Vision: Preferences for Cues, Strategies, and Aids (Part I-Perspectives from Visually Impaired Individuals). [PDF]

Brain Sci
Blokland DPH, van Loef MJE, van der Stoep N, Postma A, Overvliet KE.   +4 more
europepmc   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Il giapponismo fra teatro, cinema e pittura. Viaggio nelle fonti del primo adattamento cinematografico di Madame Butterfly

Cinergie, 2013
Maria Ida Biggi, Francesca Castellani
doaj   +1 more source