Results 31 to 40 of about 1,922,276 (292)
Curationis, 1985 Oriëntasie van ’n nuwe werknemer is noodsaaklik om angs te verlig en om horn/ haar van die inligting wat nodig is vir bevredigende werksverrigting te voorsien. Orientasieprogramme moet aangepas word by die spesifieke behoeftes van elke nuwe werknemer. Daar kan onderskei word tussen makro- en mikro-oriëntasie.
openaire +4 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Halt in Zeit-Spiel-Räumen der menschlichen Orientierung. Zum Umgang mit der Zeit im Nihilismus. Ein Impuls [PDF]
PhainomenaHold in the Leeway of Time and Space in Human Orientation. On Dealing with Time in Nihilism. An Impulse - Today, we no longer live in a world of final, fixed, absolute certainties, as traditional metaphysics once claimed.
Werner Stegmaier
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The Journal for Transdisciplinary Research in Southern Africa, 2021 no abstract available.
Janet Jarvis, Sarina de Jager
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
BMJ OpenIntroduction Autism spectrum disorder (ASD) is one of the most prevalent neurodevelopmental disorders (NDDs) and is frequently associated with psychiatric and somatic comorbidities.
Alexandra Cordina +4 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
[USF] Get Involved with USF Bound, Move-In, and Orientation
, 2020 Campus-wide email from the USF Orientation Team providing information regarding key transition events for incoming students and their family ...
Reid, Annie; Campus-wide +1 more
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