Results 71 to 80 of about 5,576,177 (380)
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Orientation and Alignment Echoes
, 2015 We present what is probably the simplest classical system featuring the echo phenomenon - a collection of randomly oriented free rotors with dispersed rotational velocities.
Averbukh, I. Sh. +8 more
core +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Flood Risk Zoning Using Fuzzy Logic Model; Case Example: Lavasanat Watershed [PDF]
دانش پیشگیری و مدیریت بحرانBackground and objective Iran is prone to various natural disasters including floods. The location of zones at risks of floods is necessary for making optimal decisions for its management.
Sayad Asghari Sareskanroud +2 more
doaj
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Predicting the Semantic Orientation of Adjectives
Annual Meeting of the Association for Computational Linguistics, 1997 We identify and validate from a large corpus constraints from conjunctions on the positive or negative semantic orientation of the conjoined adjectives.
V. Hatzivassiloglou, K. McKeown
semanticscholar +1 more source
Sexual orientation and family law [PDF]
, 2001 On 29th March 2000 the Scottish Parliament passed its fifth piece of legislation, the Adults with Incapacities (Scotland) Act 2000. One small provision tucked away in this important legislation amends the definition of "nearest relative" in the Mental ...
Norrie, Kenneth McK.
core
Orientation-Constrained Rectangular Layouts
, 2009 We construct partitions of rectangles into smaller rectangles from an input consisting of a planar dual graph of the layout together with restrictions on the orientations of edges and junctions of the layout. Such an orientation-constrained layout, if it
C.-C. Liao +9 more
core +2 more sources
Compensation of Magnetic Disturbances Improves Inertial and Magnetic Sensing of Human Body Segment Orientation [PDF]
, 2005 This paper describes a complementary Kalman filter design to estimate orientation of human body segments by fusing gyroscope, accelerometer, and magnetometer signals from miniature sensors. Ferromagnetic materials or other magnetic fields near the sensor
Baten, Chris T.M. +3 more
core +3 more sources
Molecular determinants of signal transduction in tropomyosin receptor kinases
FEBS Open Bio, EarlyView.Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source