Results 51 to 60 of about 5,605 (215)

Misdiagnosis of scrub typhus as hemorrhagic fever with renal syndrome and potential co-infection of both diseases in patients in Shandong Province, China, 2013-2014.

PLoS Neglected Tropical Diseases, 2021
BackgroundScrub typhus, caused by Orientia tsutsugamushi, an obligate intracellular gram-negative bacterium, along with hemorrhagic fever with renal syndrome (HFRS), caused by hantaviruses, are natural-focus infectious diseases prevalent in Shandong ...
Xiao-Lan Gu, Rui Qi, Wen-Qian Li, Yong-Jun Jiao, Hao Yu, Xue-Jie Yu   +5 more
doaj   +1 more source

Detection of Orientia sp. DNA in rodents from Asia, West Africa and Europe [PDF]

, 2015
Article Open AccessInternational audienceOrientia bacterium is the agent of the scrub typhus, a seriously neglected life-threatening disease in Asia. Here, we report the detection of DNA of Orientia in rodents from Europe and Africa.
Bard, Emilie, Bernard, Maria, Brouat, Carine, Bâ, Khalilou, Charbonnel, Nathalie, Dalecky, Ambroise, François Cosson, Jean, Galan, Maxime, Morand, Serge, Razzauti, Maria, Vayssier Taussat, Muriel   +10 more
core   +6 more sources

Down‐Regulation of gp96 by Orientia tsutsugamushi [PDF]

Microbiology and Immunology, 2004
Abstractgp96 plays a central role in innate as well as acquired immunity, maturation and chemotaxis of dendritic cells, Ab production, and cross‐priming, and is a peptide acceptor in endoplasmic reticulum and an accessory to peptide loading of MHC class I molecules.
Nam-Hyuk, Cho, Cheol-Young, Choi, Seung-Yong, Seong   +2 more
openaire   +2 more sources

Assessment of a Sensitive qPCR Assay Targeting a Multiple-Copy Gene to Detect Orientia tsutsugamushi DNA

Tropical Medicine and Infectious Disease, 2019
Scrub typhus is caused by an obligated intracellular organism, Orientia tsutsugamushi (Orientia). The disease was traditionally thought to be limited in the tsutsugamushi triangle.
Chien-Chung Chao, Tatyana Belinskaya, Zhiwen Zhang, Le Jiang, Wei-Mei Ching   +4 more
doaj   +1 more source

Vomocytosis: Too Much Booze, Base, or Calcium? [PDF]

, 2019
Macrophages are well known for their phagocytic activity and their role in innate immune responses. Macrophages eat non-self particles, via a variety of mechanisms, and typically break down internalized cargo into small macromolecules.
Aaron, Alvarez, Alvarez, Artavanis-Tsakonas, Bain, Ben-Abdallah, Bielska, Blackstock, Boya, Bryan, Burch, Chang, Charlier, Chen, Cheng, Chu, Circu, Cox, Davis, De Leon-Rodriguez, De Leon-Rodriguez, Denham, Di, Diamond, Doshi, Dragotakes, Drew, Erb-Downward, Erwig, Evans, Feldmesser, Franchi, Fu, Gilbert, Gordon, Guerra, Gustafson, Haka, Han, Henson, Heo, Hibbs, Hoag, Hommel, Huang, Hybiske, Iwasaki, Johnston, Kjos, Kleinschek, Kruskal, Kusner, Lei, Leopold Wager, Levitz, Levitz, Lim, Liu, Lévêque, Ma, Maderna, May, Milam, Mosser, Murdock, Murray, Myers, Müller, Nel, Nicola, Nunes, Okagaki, O’Meara, Pauwels, Qiu, Rajasingham, Russell, Samantaray, Santiago-Tirado, Singh, Smith, Stukes, Stukes, Swisher, Tucker, Vashi, Voelz, Vu, Vu, Walkey, Wang, Wang, Watkins, Weiss, Wormley, Wozniak, Yates, Yoshida, Zaragoza   +98 more
core   +2 more sources

Comprehensive Laboratory Analysis of a Scrub Typhus and H1N1 Influenza Co-Infection: A Case Report from Hainan, China

Pathogens
Co-infection of Orientia tsutsugamushi and influenza A virus complicates diagnosis and treatment in endemic regions because of overlapping clinical features and potential synergistic inflammation.
Siqi Chen, Fahui Wang, Shannan Wu, Yuanze Chen, Yi Niu, Yijia Guo, Dachuan Lin, Xiuji Cui, Ruoyan Peng, Zhao Xu, Biao Wu, Min Liao, Yongguo Du, Liyuan Zhang, Feifei Yin   +14 more
doaj   +1 more source

Concurrent Scrub Typhus, Dengue, and Leptospirosis: A Rare Triple Co‐Infection: A Case Report and Comprehensive Literature Review

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT In endemic areas, acute undifferentiated febrile illness has a wide differential with overlapping features that can lead to misdiagnosis. Although triple co‐infection with scrub typhus, dengue, and leptospirosis is extremely rare, high clinical suspicion and early detection are vital to avoid delayed treatment, multi‐organ dysfunction, and ...
Sulav Kumar Jha, Bistrit Dahal, Anamika Adhikari, Kushal Singh Basnet, Shivaditya Singh, Manaswi Acharya   +5 more
wiley   +1 more source

Active Escape of Orientia tsutsugamushi from Cellular Autophagy [PDF]

Infection and Immunity, 2013
ABSTRACT Orientia tsutsugamushi , the causative agent of scrub typhus, is an obligate intracellular pathogen. After entry into host cells, the bacterium rapidly escapes from the endosomal pathway and replicates in the cytosol of eukaryotic host cells. Here we show that O.
Youngho, Ko, Ji-Hye, Choi, Na-Young, Ha, Ik-Sang, Kim, Nam-Hyuk, Cho, Myung-Sik, Choi   +5 more
openaire   +2 more sources

Orientia tsutsugamushi in Chiggers and Small Mammals in Laos

Vector-Borne and Zoonotic Diseases, 2022
Background: Scrub typhus is a leading cause of febrile illness in Laos and accounts for a high burden of disease. There have been no previous studies on the causative agent, Orientia tsutsugamushi, in vector mites ("chiggers") or their small mammal hosts in Laos. Materials and Methods: Small mammals and free-living chiggers were trapped in districts of
Elliott, I, Kumlert, R, Thangnimitchok, N, Blacksell, SD, Tanganuchitcharnchai, A, Paris, DH, Newton, PN, Morand, S   +7 more
openaire   +5 more sources

A comparison of super‐resolution microscopy techniques for imaging tightly packed microcolonies of an obligate intracellular bacterium

Journal of Microscopy, Volume 301, Issue 2, Page 187-205, February 2026.
Abstract Conventional optical microscopy imaging of obligate intracellular bacteria is hampered by the small size of bacterial cells, tight clustering exhibited by some bacterial species and challenges relating to labelling such as background from host cells, a lack of validated reagents, and a lack of tools for genetic manipulation.
Alison J. North, Ved P. Sharma, Christina Pyrgaki, John Lim S.Y., Sharanjeet Atwal, Kittirat Saharat, Graham D. Wright, Jeanne Salje   +7 more
wiley   +1 more source