Results 51 to 60 of about 6,229 (187)

Scrub Typhus: Historic Perspective and Current Status of the Worldwide Presence of Orientia Species

Tropical Medicine and Infectious Disease, 2020
Scrub typhus and its etiological agents, Orientia species, have been around for a very long time. Historical reference to the rickettsial disease scrub typhus was first described in China (313 AD) by Hong Ge in a clinical manual (Zhouhofang) and in Japan
Allen L. Richards, Ju Jiang
doaj   +1 more source

Neglected scrub typhus: An updated review with a focus on omics technologies

Asian Pacific Journal of Tropical Medicine, 2022
Scrub typhus is a neglected disease and one of the most serious health problems in the Asia-Pacific region. The disease is caused by an obligate intracellular bacteria Orientia tsutsugamushi, which is transmitted by chigger bites or larval mite bites ...
Dixit Sharma, Ankita Sharma, Birbal Singh, Sunil Kumar, Shailender Kumar Verma   +4 more
doaj   +1 more source

Drug Design and Delivery for Intracellular Bacteria: Emerging Paradigms

Drug Development Research, Volume 86, Issue 8, December 2025.
ABSTRACT Intracellular bacteria exploit host cell niches, such as lysosomes, phagosomes, cytosol, entire cells, and even erythrocytes, to evade immune clearance and escape conventional antibiotics. These environments pose numerous therapeutic challenges, including crossing host cell membranes, navigating endosomal trafficking, tolerating acidic and ...
Babatunde Ibrahim Olowu, Maryam Ebunoluwa Zakariya, Abdulmuheez Abiola Abdulkareem, Olalekan Toheeb Okewale, Muhammad Halima Idris, Halimah Oluwayemisi Olayiwola   +5 more
wiley   +1 more source

Vomocytosis: Too Much Booze, Base, or Calcium? [PDF]

, 2019
Macrophages are well known for their phagocytic activity and their role in innate immune responses. Macrophages eat non-self particles, via a variety of mechanisms, and typically break down internalized cargo into small macromolecules.
Aaron, Alvarez, Alvarez, Artavanis-Tsakonas, Bain, Ben-Abdallah, Bielska, Blackstock, Boya, Bryan, Burch, Chang, Charlier, Chen, Cheng, Chu, Circu, Cox, Davis, De Leon-Rodriguez, De Leon-Rodriguez, Denham, Di, Diamond, Doshi, Dragotakes, Drew, Erb-Downward, Erwig, Evans, Feldmesser, Franchi, Fu, Gilbert, Gordon, Guerra, Gustafson, Haka, Han, Henson, Heo, Hibbs, Hoag, Hommel, Huang, Hybiske, Iwasaki, Johnston, Kjos, Kleinschek, Kruskal, Kusner, Lei, Leopold Wager, Levitz, Levitz, Lim, Liu, Lévêque, Ma, Maderna, May, Milam, Mosser, Murdock, Murray, Myers, Müller, Nel, Nicola, Nunes, Okagaki, O’Meara, Pauwels, Qiu, Rajasingham, Russell, Samantaray, Santiago-Tirado, Singh, Smith, Stukes, Stukes, Swisher, Tucker, Vashi, Voelz, Vu, Vu, Walkey, Wang, Wang, Watkins, Weiss, Wormley, Wozniak, Yates, Yoshida, Zaragoza   +98 more
core   +2 more sources

Silent Threat: Multi‐Organ Failure in Neonatal Scrub Typhus Without Traditional Markers

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT Scrub typhus, an acute zoonotic disease from Orientia tsutsugamushi, is uncommon in newborns and presents atypical symptoms. Untimely diagnosis and treatment can lead to a prolonged and potentially fatal course. Early diagnosis and treatment are essential for better patient outcomes.
Li Hu, Shuyan Li, Fangjian Gao, Shiguang Diao, Xiaoyan Liu, Jianwu Qiu   +5 more
wiley   +1 more source

Diagnosis of Rickettsial infection by Multiplex Real-time PCR in Febrile Pediatric Patients Admitted in a Tertiary Care Hospital at Chennai, South India

Journal of Pure and Applied Microbiology
Rickettsioses caused by Rickettsia and Orientia spp. are the re-emerging diseases in India, which are grossly underdiagnosed, particularly among children.
Rajagopal Murali, Sivasambo Kalpana, Karthick Shanmugam, Prabu Dhandapani   +3 more
doaj   +1 more source

Scrub Typhus Outbreak in Chonburi Province, Central Thailand, 2013

Emerging Infectious Diseases, 2018
Investigation of a scrub typhus outbreak in Thailand during September 2013 found that 9.1% of Thai soldiers and 11.1% of residents living in areas surrounding training sites had antibodies against the causative agent, Orientia tsutsugamushi.
Wuttikon Rodkvamtook, Narupon Kuttasingkee, Piyada Linsuwanon, Yutthapong Sudsawat, Allen L. Richards, Maneerat Somsri, Noppadon Sangjun, Chien-Chung Chao, Silas Davidson, Elizabeth Wanja, Jariyanart Gaywee   +10 more
doaj   +1 more source

A Multiplex PCR assay for a differential diagnostic of rickettsiosis, Lyme disease and scrub typhus

Journal of Vector Borne Diseases, 2022
Background & objectives: Coexistence of tick-borne diseases in some regions in Latin America makes the diagnosis difficult due to shared initial signs and symptoms. Rickettsiosis, Lyme disease and recently, scrub typhus are gaining more importance.
Gaspar Peniche-Lara, Isamara Moo-Salazar, Karla Dzul-Rosado   +2 more
doaj   +1 more source

The Effect of Climate Change on Emergence and Evolution of Zoonotic Diseases in Asia

Zoonoses and Public Health, Volume 72, Issue 7, Page 587-611, November 2025.
ABSTRACT As the climate of Asia changes under the influence of global warming, the incidence and spatial distribution of known zoonoses will evolve, and new zoonoses are expected to emerge as a result of greater exposure to organisms which currently occur only in wildlife.
Roger S. Morris, Masako Wada
wiley   +1 more source

Metabolic responses to Orientia tsutsugamushi infection in a mouse model. [PDF]

PLoS Neglected Tropical Diseases, 2015
Tsutsugamushi disease is an infectious disease transmitted to humans through the bite of the Orientia tsutsugamushi-infected chigger mite; however, host-pathogen interactions and the precise mechanisms of damage in O.
Jeeyoun Jung, Youngae Jung, Byoungchul Gill, Changhun Kim, Kyu-Jam Hwang, Young-Ran Ju, Hye-Ja Lee, Hyuk Chu, Geum-Sook Hwang   +8 more
doaj   +1 more source