Results 51 to 60 of about 5,617 (192)

Rapid, simple, and sensitive detection of the ompB gene of spotted fever group rickettsiae by loop-mediated isothermal amplification [PDF]

, 2012
BACKGROUND: Spotted fever caused spotted fever group rickettsiae (SFGR) is prevalent throughout China. In this study, we describe a rapid, simple, and sensitive loop-mediated isothermal amplification (LAMP) assay targeting the ompB gene of spotted fever ...
Guiqiang Wang, Lei Pan, Lijuan Zhang, Qinghui Liu   +3 more
core   +1 more source

Down‐Regulation of gp96 by Orientia tsutsugamushi [PDF]

Microbiology and Immunology, 2004
Abstractgp96 plays a central role in innate as well as acquired immunity, maturation and chemotaxis of dendritic cells, Ab production, and cross‐priming, and is a peptide acceptor in endoplasmic reticulum and an accessory to peptide loading of MHC class I molecules.
Nam-Hyuk, Cho, Cheol-Young, Choi, Seung-Yong, Seong   +2 more
openaire   +2 more sources

Molecular characterization of Orientia tsutsugamushi causing scrub typhus among febrile patients in north-central Bangladesh

New Microbes and New Infections, 2019
Scrub typhus is a mite-borne rickettsial disease caused by Orientia tsutsugamushi, which is endemic in Asia Pacific region. In this study, infection rate and molecular epidemiologic traits of O.
M.M. Al Amin, S.K. Paul, M.S. Aung, A. Paul, M.A. Aziz, N.A. Khan, A.K.M.F. Haque, F. Ahamed, A. Melan, S.R. Sarker, M.A. Hossain, S. Ahmed, S.A. Nasreen, N. Haque, N. Kobayashi   +14 more
doaj   +1 more source

Neglected scrub typhus: An updated review with a focus on omics technologies

Asian Pacific Journal of Tropical Medicine, 2022
Scrub typhus is a neglected disease and one of the most serious health problems in the Asia-Pacific region. The disease is caused by an obligate intracellular bacteria Orientia tsutsugamushi, which is transmitted by chigger bites or larval mite bites ...
Dixit Sharma, Ankita Sharma, Birbal Singh, Sunil Kumar, Shailender Kumar Verma   +4 more
doaj   +1 more source

Detection of Orientia sp. DNA in rodents from Asia, West Africa and Europe [PDF]

, 2015
Article Open AccessInternational audienceOrientia bacterium is the agent of the scrub typhus, a seriously neglected life-threatening disease in Asia. Here, we report the detection of DNA of Orientia in rodents from Europe and Africa.
Bard, Emilie, Bernard, Maria, Brouat, Carine, Bâ, Khalilou, Charbonnel, Nathalie, Dalecky, Ambroise, François Cosson, Jean, Galan, Maxime, Morand, Serge, Razzauti, Maria, Vayssier Taussat, Muriel   +10 more
core   +6 more sources

Comprehensive Laboratory Analysis of a Scrub Typhus and H1N1 Influenza Co-Infection: A Case Report from Hainan, China

Pathogens
Co-infection of Orientia tsutsugamushi and influenza A virus complicates diagnosis and treatment in endemic regions because of overlapping clinical features and potential synergistic inflammation.
Siqi Chen, Fahui Wang, Shannan Wu, Yuanze Chen, Yi Niu, Yijia Guo, Dachuan Lin, Xiuji Cui, Ruoyan Peng, Zhao Xu, Biao Wu, Min Liao, Yongguo Du, Liyuan Zhang, Feifei Yin   +14 more
doaj   +1 more source

Scrub Typhus: Historic Perspective and Current Status of the Worldwide Presence of Orientia Species

Tropical Medicine and Infectious Disease, 2020
Scrub typhus and its etiological agents, Orientia species, have been around for a very long time. Historical reference to the rickettsial disease scrub typhus was first described in China (313 AD) by Hong Ge in a clinical manual (Zhouhofang) and in Japan
Allen L. Richards, Ju Jiang
doaj   +1 more source

Vomocytosis: Too Much Booze, Base, or Calcium? [PDF]

, 2019
Macrophages are well known for their phagocytic activity and their role in innate immune responses. Macrophages eat non-self particles, via a variety of mechanisms, and typically break down internalized cargo into small macromolecules.
Aaron, Alvarez, Alvarez, Artavanis-Tsakonas, Bain, Ben-Abdallah, Bielska, Blackstock, Boya, Bryan, Burch, Chang, Charlier, Chen, Cheng, Chu, Circu, Cox, Davis, De Leon-Rodriguez, De Leon-Rodriguez, Denham, Di, Diamond, Doshi, Dragotakes, Drew, Erb-Downward, Erwig, Evans, Feldmesser, Franchi, Fu, Gilbert, Gordon, Guerra, Gustafson, Haka, Han, Henson, Heo, Hibbs, Hoag, Hommel, Huang, Hybiske, Iwasaki, Johnston, Kjos, Kleinschek, Kruskal, Kusner, Lei, Leopold Wager, Levitz, Levitz, Lim, Liu, Lévêque, Ma, Maderna, May, Milam, Mosser, Murdock, Murray, Myers, Müller, Nel, Nicola, Nunes, Okagaki, O’Meara, Pauwels, Qiu, Rajasingham, Russell, Samantaray, Santiago-Tirado, Singh, Smith, Stukes, Stukes, Swisher, Tucker, Vashi, Voelz, Vu, Vu, Walkey, Wang, Wang, Watkins, Weiss, Wormley, Wozniak, Yates, Yoshida, Zaragoza   +98 more
core   +2 more sources

A comparison of super‐resolution microscopy techniques for imaging tightly packed microcolonies of an obligate intracellular bacterium

Journal of Microscopy, Volume 301, Issue 2, Page 187-205, February 2026.
Abstract Conventional optical microscopy imaging of obligate intracellular bacteria is hampered by the small size of bacterial cells, tight clustering exhibited by some bacterial species and challenges relating to labelling such as background from host cells, a lack of validated reagents, and a lack of tools for genetic manipulation.
Alison J. North, Ved P. Sharma, Christina Pyrgaki, John Lim S.Y., Sharanjeet Atwal, Kittirat Saharat, Graham D. Wright, Jeanne Salje   +7 more
wiley   +1 more source

A Rare and Severe Multisystem Cascade of AKI, ARDS, and Septic Shock Leading to Acalculous Cholecystitis in a Young Scrub Typhus Patient: A Case Report From Nepal

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Scrub typhus, caused by Orientia tsutsugamushi, is an acute febrile illness prevalent in Nepal with a wide spectrum of clinical presentations. Severe forms can lead to multiorgan dysfunction, including acute kidney injury (AKI), acute respiratory distress syndrome (ARDS), septic shock, and rarely, acalculous cholecystitis.
Prabhat Kaphle, Maya Upadhyaya, Sarjan Shrestha, Amrita Shrestha, Dhanlaxmi Giri, Kamal Hamal, Liladhar Ojha   +6 more
wiley   +1 more source