Results 31 to 40 of about 3,386 (131)

Murine models of scrub typhus associated with host control of Orientia tsutsugamushi infection. [PDF]

PLoS Neglected Tropical Diseases, 2017
BACKGROUND:Scrub typhus, a febrile illness of substantial incidence and mortality, is caused by infection with the obligately intracellular bacterium Orientia tsutsugamushi.
Nicole L Mendell, Donald H Bouyer, David H Walker   +2 more
doaj   +1 more source

Acute Febrile Illness With Triple Co‐Infection: A Case Report on the Diagnostic Challenges of Overlapping Febrile Illnesses

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT A 35‐year‐old female presented with 5 days of fever, fatigue, and myalgia during the post‐monsoon season at Damak Hospital, Jhapa, Nepal. Clinical examination revealed fever (102.7°F), tachycardia (110 bpm), and crackles in the right lower lung field.
Santosh Basyal, Rahul Parajuli, Dipendra Prasad Yadav, Shardul Bhattarai, Kritick Bhandari, Shrijana Basyal, Gul Zaman, Rohit Parajuli   +7 more
wiley   +1 more source

Diagnosis of Rickettsial infection by Multiplex Real-time PCR in Febrile Pediatric Patients Admitted in a Tertiary Care Hospital at Chennai, South India

Journal of Pure and Applied Microbiology
Rickettsioses caused by Rickettsia and Orientia spp. are the re-emerging diseases in India, which are grossly underdiagnosed, particularly among children.
Rajagopal Murali, Sivasambo Kalpana, Karthick Shanmugam, Prabu Dhandapani   +3 more
doaj   +1 more source

Scrub Typhus: Historic Perspective and Current Status of the Worldwide Presence of Orientia Species

Tropical Medicine and Infectious Disease, 2020
Scrub typhus and its etiological agents, Orientia species, have been around for a very long time. Historical reference to the rickettsial disease scrub typhus was first described in China (313 AD) by Hong Ge in a clinical manual (Zhouhofang) and in Japan
Allen L. Richards, Ju Jiang
doaj   +1 more source

Single‐cell profiling of peripheral blood reveals acute‐phase immune dysregulation in human scrub typhus

iMeta, Volume 5, Issue 4, August 2026.
Integrated single‐cell RNA sequencing, spectral flow cytometry, immune‐receptor repertoire profiling, and plasma proteomics revealed coordinated peripheral immune remodeling during acute scrub typhus. Patients exhibited expansion of cytotoxic, clonally amplified CD8+ T cells with exhaustion‐associated features, depletion and apoptosis of CD4+ T cells ...
Yijia Guo, Yi Niu, Nihui Zhang, Xiao Han, Liyuan Zhang, Yongguo Du, Lifen Han, Xiuying Tian, Zhao Xu, Gaoyu Wang, Kwok‐Yung Yuen, Jasper Fuk‐Woo Chan, Dahua Xu, Feifei Yin   +13 more
wiley   +1 more source

Neglected scrub typhus: An updated review with a focus on omics technologies

Asian Pacific Journal of Tropical Medicine, 2022
Scrub typhus is a neglected disease and one of the most serious health problems in the Asia-Pacific region. The disease is caused by an obligate intracellular bacteria Orientia tsutsugamushi, which is transmitted by chigger bites or larval mite bites ...
Dixit Sharma, Ankita Sharma, Birbal Singh, Sunil Kumar, Shailender Kumar Verma   +4 more
doaj   +1 more source

Searching for the beasts in the archive as methodological praxis

Geographical Research, Volume 64, Issue 3, August 2026.
This article offers searching for the beasts in the archive as a methodological tool available to researchers invested in both anticolonialism and antianthropocentrism. By focusing on three basic units of reference—categories, histories, and borders—the article shows how searching for the beasts unsettles some taken‐for‐granted assumptions that ...
Senel Wanniarachchi
wiley   +1 more source

Korat‐Scrub Typhus Score: A Clinical Tool for Predicting Scrub Typhus in Patients With Acute Undifferentiated Febrile Illness

Tropical Medicine &International Health, Volume 31, Issue 8, Page 1066-1072, August 2026.
ABSTRACT Objective Scrub typhus is a major cause of acute undifferentiated febrile illness (AUFI) in the Asia–Pacific region. Nonspecific presentation, limited diagnostic accuracy and delayed treatment increase morbidity and mortality. This study aimed to develop a simple clinical score for early diagnosis in adults with AUFI. Methods A cross‐sectional
Wilawan Thipmontree, Ekkarat Wongsawat, Saowaluk Silpasakorn, Yupin Suputtamongkol   +3 more
wiley   +1 more source

Scrub Typhus Outbreak in Chonburi Province, Central Thailand, 2013

Emerging Infectious Diseases, 2018
Investigation of a scrub typhus outbreak in Thailand during September 2013 found that 9.1% of Thai soldiers and 11.1% of residents living in areas surrounding training sites had antibodies against the causative agent, Orientia tsutsugamushi.
Wuttikon Rodkvamtook, Narupon Kuttasingkee, Piyada Linsuwanon, Yutthapong Sudsawat, Allen L. Richards, Maneerat Somsri, Noppadon Sangjun, Chien-Chung Chao, Silas Davidson, Elizabeth Wanja, Jariyanart Gaywee   +10 more
doaj   +1 more source

Synthetic Ligands of Myeloid C‐Type Lectin Receptors

ChemBioChem, Volume 27, Issue 13, 14 July 2026.
Binding of ligands to C‐type lectin receptors (CLRs) on myeloid cells can lead to an array of cellular responses. Exploitation of these receptors for therapeutic purposes requires high‐affinity ligands. This review surveys the diversity of synthetic ligands of myeloid CLRs in the context of binding, signaling, and downstream effects, as well as ...
James Suri, Bernd Lepenies
wiley   +1 more source