Results 51 to 60 of about 3,386 (131)

Orientia tsutsugamushi, the agent of scrub typhus

WikiJournal of Medicine, 2019
Orientia tsutsugamushi is a mite-borne bacterium belonging to the family Rickettsiaceae and is responsible for the disease scrub typhus in humans. It is an obligate intracellular parasite of trombiculid mites, in which natural transmission is maintained ...
Kholhring Lalchhandama
doaj   +1 more source

Surveillance of Zoonotic Pathogens in Small Mammals Across Forests With Different Levels of Anthropization in Eastern France

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The emergence of infectious diseases associated with land‐use changes is well‐documented. However, the presence and dynamics of zoonotic pathogens in small mammals within European forests, whether from rural development or urban greening, remain underexplored.
Marie Bouilloud, Maxime Galan, Anaïs Bordes, Caroline Tatard, Philippe Gauthier, Julien Pradel, Guillaume Castel, Hussein Alburkat, Lara Dutra, Tarja Sironen, Clémence Galon, Sara Moutailler, Zorée Djelouadji, Benjamin Roche, Nathalie Charbonnel, Javier Millán   +15 more
wiley   +1 more source

Orientia tsutsugamushi in Eschars from Scrub Typhus Patients

Emerging Infectious Diseases, 2006
To verify the value of eschars for the diagnosis of scrub typhus and to characterize genotypes of Orientia tsutsugamushi in patients, we examined eschars and blood specimens of 7 patients from Shandong Province, People's Republic of China, for O ...
Yun-Xi Liu, Wu-Chun Cao, Yuan Gao, Jing-Lan Zhang, Zhan-Qing Yang, Zhong-Tang Zhao, Janet Foley   +6 more
doaj   +1 more source

Diagnosis of severe scrub typhus infection by next-generation sequencing:a case report

BMC Infectious Diseases, 2020
Background Scrub typhus is an acute febrile illness, which was caused by Orientia tsutsugamushi and transmitted through the bite of chiggers. The diagnosis of scrub typhus could be missed diagnosis due to the absence of the pathognomonic eschar.
Jie Chen, Xu-dong Zheng, Qi-he Dai, Wei-li Hong, You-peng Li, Rui Chen, Bing-bing Ye, Xiao-jie Mo, Peng Cui, Zhan-wei Ruan   +9 more
doaj   +1 more source

A Rare and Severe Multisystem Cascade of AKI, ARDS, and Septic Shock Leading to Acalculous Cholecystitis in a Young Scrub Typhus Patient: A Case Report From Nepal

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Scrub typhus, caused by Orientia tsutsugamushi, is an acute febrile illness prevalent in Nepal with a wide spectrum of clinical presentations. Severe forms can lead to multiorgan dysfunction, including acute kidney injury (AKI), acute respiratory distress syndrome (ARDS), septic shock, and rarely, acalculous cholecystitis.
Prabhat Kaphle, Maya Upadhyaya, Sarjan Shrestha, Amrita Shrestha, Dhanlaxmi Giri, Kamal Hamal, Liladhar Ojha   +6 more
wiley   +1 more source

Drug Design and Delivery for Intracellular Bacteria: Emerging Paradigms

Drug Development Research, Volume 86, Issue 8, December 2025.
ABSTRACT Intracellular bacteria exploit host cell niches, such as lysosomes, phagosomes, cytosol, entire cells, and even erythrocytes, to evade immune clearance and escape conventional antibiotics. These environments pose numerous therapeutic challenges, including crossing host cell membranes, navigating endosomal trafficking, tolerating acidic and ...
Babatunde Ibrahim Olowu, Maryam Ebunoluwa Zakariya, Abdulmuheez Abiola Abdulkareem, Olalekan Toheeb Okewale, Muhammad Halima Idris, Halimah Oluwayemisi Olayiwola   +5 more
wiley   +1 more source

Silent Threat: Multi‐Organ Failure in Neonatal Scrub Typhus Without Traditional Markers

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT Scrub typhus, an acute zoonotic disease from Orientia tsutsugamushi, is uncommon in newborns and presents atypical symptoms. Untimely diagnosis and treatment can lead to a prolonged and potentially fatal course. Early diagnosis and treatment are essential for better patient outcomes.
Li Hu, Shuyan Li, Fangjian Gao, Shiguang Diao, Xiaoyan Liu, Jianwu Qiu   +5 more
wiley   +1 more source

Development of a rapid and visual nucleotide detection method for a Chinese epidemic strain of Orientia tsutsugamushi based on recombinase polymerase amplification assay and lateral flow test

International Journal of Infectious Diseases, 2018
Objectives: Orientia tsutsugamushi is an obligate intracellular pathogen that causes scrub typhus. Diagnosing scrub typhus remains a challenge, and a sensitive, specific, simple, and rapid diagnostic test is still needed.
Yong Qi, Qiong Yin, Yinxiu Shao, Min Cao, Suqin Li, Hongxia Chen, Wanpeng Shen, Jixian Rao, Jiameng Li, Xiaoling Li, Yu Sun, Yu Lin, Yi Deng, Wenwen Zeng, Shulong Zheng, Suyun Liu, Yuexi Li   +16 more
doaj   +1 more source

Infection of Rodents by Orientia tsutsugamushi, the Agent of Scrub Typhus in Relation to Land Use in Thailand

Tropical Medicine and Infectious Disease, 2017
The relationship between land use structures and occurrence of scrub typhus agent, Orientia tsutsugamushi infection in small wild mammals was conducted in three provinces of Thailand: Buriram, Loei, and Nan. Orientia tsutsugamushi detection was performed
Kittipong Chaisiri, Jean-François Cosson, Serge Morand   +2 more
doaj   +1 more source

Plasmodium Vivax Can Only Be Responsible for GBS if All Other Triggers Have Been Ruled Out

Clinical Case Reports, Volume 14, Issue 4, April 2026.
Josef Finsterer
wiley   +1 more source