Results 71 to 80 of about 4,261 (215)

New Orientia tsutsugamushi Strain from Scrub Typhus in Australia

Emerging Infectious Diseases, 1998
In a recent case of scrub typhus in Australia, Orientia tsutsugamushi isolated from the patient's blood was tested by sequence analysis of the 16S rDNA gene. The sequence showed a strain of O. tsutsugamushi that was quite different from the classic Karp,
Dimitri M. Odorico, Stephen R. Graves, Bart J. Currie, Julian Catmull, Zoltan Nack, Sharon Ellis, Ling Wang, David J. Miller   +7 more
doaj   +1 more source

A Rare and Severe Multisystem Cascade of AKI, ARDS, and Septic Shock Leading to Acalculous Cholecystitis in a Young Scrub Typhus Patient: A Case Report From Nepal

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Scrub typhus, caused by Orientia tsutsugamushi, is an acute febrile illness prevalent in Nepal with a wide spectrum of clinical presentations. Severe forms can lead to multiorgan dysfunction, including acute kidney injury (AKI), acute respiratory distress syndrome (ARDS), septic shock, and rarely, acalculous cholecystitis.
Prabhat Kaphle, Maya Upadhyaya, Sarjan Shrestha, Amrita Shrestha, Dhanlaxmi Giri, Kamal Hamal, Liladhar Ojha   +6 more
wiley   +1 more source

CD8+ T cells provide immune protection against murine disseminated endotheliotropic Orientia tsutsugamushi infection. [PDF]

PLoS Neglected Tropical Diseases, 2017
Scrub typhus, caused by a Gram-negative obligately intracellular coccobacillus, Orientia tsutsugamushi, is a long neglected but important tropical disease. Orientia tsutsugamushi causes illness in one million people each year, and 1 billion people are at
Guang Xu, Nicole L Mendell, Yuejin Liang, Thomas R Shelite, Yenny Goez-Rivillas, Lynn Soong, Donald H Bouyer, David H Walker   +7 more
doaj   +1 more source

Vector and rodent surveillance for Orientia tsutsugamushi in north India

Journal of Vector Borne Diseases, 2022
Background & objectives: Scrub typhus or chigger borne typhus, caused by Orientia tsutsugamushi is an emerging vector-borne disease as large numbers of cases have been reported in various tropical countries. It is transmitted to humans through bites of infected chiggers (larval mites). The
Taruna Kaura, Jasleen Kaur, Kamlesh Bisht, Shriya Goel, PVM Lakshmi, Gagandeep Singh Grover, Abhishek Mewara, Manisha Biswal   +7 more
openaire   +3 more sources

Drug Design and Delivery for Intracellular Bacteria: Emerging Paradigms

Drug Development Research, Volume 86, Issue 8, December 2025.
ABSTRACT Intracellular bacteria exploit host cell niches, such as lysosomes, phagosomes, cytosol, entire cells, and even erythrocytes, to evade immune clearance and escape conventional antibiotics. These environments pose numerous therapeutic challenges, including crossing host cell membranes, navigating endosomal trafficking, tolerating acidic and ...
Babatunde Ibrahim Olowu, Maryam Ebunoluwa Zakariya, Abdulmuheez Abiola Abdulkareem, Olalekan Toheeb Okewale, Muhammad Halima Idris, Halimah Oluwayemisi Olayiwola   +5 more
wiley   +1 more source

Orientia tsutsugamushi [PDF]

Trends in Microbiology, 2020
Jantana Wongsantichon, Yanin Jaiyen, Sabine Dittrich, Jeanne Salje   +3 more
openaire   +3 more sources

Silent Threat: Multi‐Organ Failure in Neonatal Scrub Typhus Without Traditional Markers

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT Scrub typhus, an acute zoonotic disease from Orientia tsutsugamushi, is uncommon in newborns and presents atypical symptoms. Untimely diagnosis and treatment can lead to a prolonged and potentially fatal course. Early diagnosis and treatment are essential for better patient outcomes.
Li Hu, Shuyan Li, Fangjian Gao, Shiguang Diao, Xiaoyan Liu, Jianwu Qiu   +5 more
wiley   +1 more source

Analysis of Prevalent Orientia tsutsugamushi in Aichi Prefecture

Journal of the Japanese Association for Infectious Diseases, 1999
Orientia tsutsugamushi was isolated from one of 8 patients' sera in Aichi Prefecture, and was identified to have the same antigenicity with the KN-2 strain (KN-2 like) based on the reactivity with 13 types of strain-specific or cross-reactive monoclonal antibodies to Karp, Gilliam, and Kato strains.
YAMASHITA, Teruo, MORISHITA, Takayuki, TSUZUKI, Hideaki, SAKAE, Kenji, SUZUKI, Yasumoto, KADOSAKA, Teruki, KASUYA, Shiro   +6 more
openaire   +3 more sources

The Effect of Climate Change on Emergence and Evolution of Zoonotic Diseases in Asia

Zoonoses and Public Health, Volume 72, Issue 7, Page 587-611, November 2025.
ABSTRACT As the climate of Asia changes under the influence of global warming, the incidence and spatial distribution of known zoonoses will evolve, and new zoonoses are expected to emerge as a result of greater exposure to organisms which currently occur only in wildlife.
Roger S. Morris, Masako Wada
wiley   +1 more source

Active Escape of Orientia tsutsugamushi from Cellular Autophagy [PDF]

Infection and Immunity, 2013
ABSTRACT Orientia tsutsugamushi , the causative agent of scrub typhus, is an obligate intracellular pathogen. After entry into host cells, the bacterium rapidly escapes from the endosomal pathway and replicates in the cytosol of eukaryotic host cells. Here we show that O.
Youngho, Ko, Ji-Hye, Choi, Na-Young, Ha, Ik-Sang, Kim, Nam-Hyuk, Cho, Myung-Sik, Choi   +5 more
openaire   +2 more sources