Results 71 to 80 of about 5,639 (203)

Scrub Typhus Outbreak in Chonburi Province, Central Thailand, 2013

open access: yesEmerging Infectious Diseases, 2018
Investigation of a scrub typhus outbreak in Thailand during September 2013 found that 9.1% of Thai soldiers and 11.1% of residents living in areas surrounding training sites had antibodies against the causative agent, Orientia tsutsugamushi.
Wuttikon Rodkvamtook   +10 more
doaj   +1 more source

A Metabolic Dependency for Host Isoprenoids in the Obligate Intracellular Pathogen Rickettsia parkeri Underlies a Sensitivity to the Statin Class of Host-Targeted Therapeutics. [PDF]

open access: yes, 2019
Gram-negative bacteria in the order Rickettsiales have an obligate intracellular growth requirement, and some species cause human diseases such as typhus and spotted fever.
Ahyong, Vida   +4 more
core   +2 more sources

Identification of Potential Therapeutic Agents for Primary Amebic Meningoencephalitis Using Text Mining and Bioinformatics Analyses

open access: yesAnalytical Cellular Pathology, Volume 2026, Issue 1, 2026.
Naegleria fowleri, the brain‐eating ameba, causes primary amebic meningoencephalitis (PAM), a fatal infectious disease that affects the central nervous system (CNS). We aimed to evaluate the functions and potential drugs targeting PAM using text mining and bioinformatics analyses.
Eun Jung Sohn   +3 more
wiley   +1 more source

Neglected scrub typhus: An updated review with a focus on omics technologies

open access: yesAsian Pacific Journal of Tropical Medicine, 2022
Scrub typhus is a neglected disease and one of the most serious health problems in the Asia-Pacific region. The disease is caused by an obligate intracellular bacteria Orientia tsutsugamushi, which is transmitted by chigger bites or larval mite bites ...
Dixit Sharma   +4 more
doaj   +1 more source

Scrub Typhus Presenting as Acute Mastoiditis. [PDF]

open access: yes, 2014
Scrub typhus, a zoonosis, is known to present with varied clinical presentation. We present a case of acute mastoiditis who did not respond to conventional antibiotic therapy.
Kumar, S, Lal, B, Minhas, RS, Sharma, DR
core   +1 more source

Surveillance of Zoonotic Pathogens in Small Mammals Across Forests With Different Levels of Anthropization in Eastern France

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The emergence of infectious diseases associated with land‐use changes is well‐documented. However, the presence and dynamics of zoonotic pathogens in small mammals within European forests, whether from rural development or urban greening, remain underexplored.
Marie Bouilloud   +15 more
wiley   +1 more source

New Orientia tsutsugamushi Strain from Scrub Typhus in Australia

open access: yesEmerging Infectious Diseases, 1998
In a recent case of scrub typhus in Australia, Orientia tsutsugamushi isolated from the patient's blood was tested by sequence analysis of the 16S rDNA gene. The sequence showed a strain of O. tsutsugamushi that was quite different from the classic Karp,
Dimitri M. Odorico   +7 more
doaj   +1 more source

CD8+ T cells provide immune protection against murine disseminated endotheliotropic Orientia tsutsugamushi infection. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2017
Scrub typhus, caused by a Gram-negative obligately intracellular coccobacillus, Orientia tsutsugamushi, is a long neglected but important tropical disease. Orientia tsutsugamushi causes illness in one million people each year, and 1 billion people are at
Guang Xu   +7 more
doaj   +1 more source

Causes of non-malarial fever in Laos: a prospective study [PDF]

open access: yes, 2013
Background Because of reductions in the incidence of Plasmodium falciparum malaria in Laos, identifi cation of the causes of fever in people without malaria, and discussion of the best empirical treatment options, are urgently needed.
Castonguay-Vanier, Josée   +19 more
core  

The nucleotide addition cycle of RNA polymerase is controlled by two molecular hinges in the Bridge Helix domain [PDF]

open access: yes, 2010
Background Cellular RNA polymerases (RNAPs) are complex molecular machines that combine catalysis with concerted conformational changes in the active center.
Robert OJ Weinzierl
core   +4 more sources

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