Scrub typhus is a potentially severe rickettsiosis, caused by Orientia tsutsugamushi in the Asia-Pacific region. Recently, however, two distinct pathogens, “Candidatus Orientia chuto” and “Candidatus Orientia chiloensis”, have been discovered in the ...
Ju Jiang +10 more
doaj +1 more source
Analysis of Orientia tsutsugamushi promoter activity [PDF]
ABSTRACT Orientia tsutsugamushi is an obligate intracellular bacterium that causes scrub typhus, a potentially fatal rickettsiosis, and for which no genetic tools exist. Critical to addressing this technical gap is to identify promoters for driving expression of antibiotic resistance and fluorescence reporter genes in O.
Jason R Hunt, Jason A Carlyon
openaire +2 more sources
Hematogenously disseminated Orientia tsutsugamushi-infected murine model of scrub typhus [corrected]. [PDF]
Orientia tsutsugamushi, the etiologic agent of scrub typhus, is a mite-borne rickettsia transmitted by the parasitic larval stage of trombiculid mites. Approximately one-third of the world's population is at risk of infection with Orientia tsutsugamushi,
Thomas R Shelite +8 more
doaj +1 more source
Molecular Epidemiology and Genetic Diversity of Orientia tsutsugamushi From Patients and Small Mammals in Xiangyun County, Yunnan Province, China. [PDF]
Scrub typhus is caused by Orientia tsutsugamushi (OT). In this study, the detection rates of OT in patients and small mammals were 28.13% (18/64) and 13.98% (13/93), respectively. Nine full‐length 56‐kDa TSA genes were identified, comprising four distinct genotypes: Karp‐like (n = 3), Kato‐like (n = 3), Gilliam (n = 2), and TA763 (n = 1). Recombination
Chen L +9 more
europepmc +2 more sources
Shotgun proteomics of Orientia tsutsugamushi [PDF]
Orientia tsutsugamushi is one of the obligate intracellular bacteria, and causes Tsutsugamushi disease (scrub typhus). The whole genome sequence of Boryong strain revealed some characteristics of this bacterium, such as a type IV secretion system, many histidine kinases, SpoT, Tra, and ankyrin repeatand tetratricopeptide repeat (TPR)-containing ...
Ogawa, M. +7 more
openaire +2 more sources
Indoor and Outdoor Rodent Hosts of Orientia tsutsugamushi, Shandong Province, China
During December 2012–July 2016, we tested small indoor and outdoor mammals in Qingdao, China, for Orientia tsutsugamushi infection. We found that outdoor Apodemus agrarius mice, Cricetulus barabensis hamsters, and Niviventer confucianus rats, as well as ...
Fei Li +5 more
doaj +1 more source
Symbiosis in an overlooked microcosm: a systematic review of the bacterial flora of mites [PDF]
A dataset of bacterial diversity found in mites was compiled from 193 publications (from 1964 to January 2015). A total of 143 mite species belonging to the 3 orders (Mesostigmata, Sarcoptiformes and Trombidiformes) were recorded and found to be ...
Chaisiri, Kittipong +3 more
core +2 more sources
A case of Henoch-Schönlein purpura associated with scrub typhus
Background Henoch-Schönlein purpura (HSP) may be caused by several allergens. However, to date, HSP caused by Orientia tsutsugamushi has not been reported. Here, we report an unusual rash with features of HSP caused by Orientia tsutsugamushi.
Jae Hyoung Im +7 more
doaj +1 more source
Orientia tsutsugamushi ankyrin repeat-containing protein family members are Type 1 secretion system substrates that traffic to the host cell endoplasmic reticulum [PDF]
Scrub typhus is an understudied, potentially fatal infection that threatens one billion persons in the Asia-Pacific region. How the causative obligate intracellular bacterium, Orientia tsutsugamushi, facilitates its intracellular survival and ...
Beare, Paul A. +10 more
core +3 more sources
Rapid increase of scrub typhus incidence in Guangzhou, southern China, 2006-2014 [PDF]
Background: In the last decade, scrub typhus (ST) has been emerging or re-emerging in some areas of Asia, including Guangzhou, one of the most affected endemic areas of ST in China.
Cao, W.-C. (Wu-Chun) +14 more
core +4 more sources

