Results 71 to 80 of about 205,980 (312)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Age-Related Decline in Disengaging Spatial Attention in Physiological Aging

open access: yesBrain Sciences
Background/Objectives: Attention is a complex process involving various components such as alerting, orienting, and resolving conflicts. These components have been widely examined using the Attention Network Test (ANT), which has also been used to ...
Tiziana Pedale   +3 more
doaj   +1 more source

Illuminating the Neural Circuits Underlying Orienting of Attention

open access: yesVision, 2019
Human neuroimaging has revealed brain networks involving frontal and parietal cortical areas as well as subcortical areas, including the superior colliculus and pulvinar, which are involved in orienting to sensory stimuli.
Michael I. Posner, Cristopher M. Niell
doaj   +1 more source

Orienting Activity of the Subject as a Mechanism for Instruction, Learning and Development

open access: yesPsychology in Russia: State of Art, 2022
Background. The 120th anniversary was celebrated in 2022 of the birth of the outstanding Soviet scientist P.Ya. Galperin (1902–1988), who made a signi# cant contribution to the development of Russian psychology. Objective. To analyze the signi# cance of
Galina V. Burmenskaya
doaj   +1 more source

The multisensory body revealed through its cast shadows [PDF]

open access: yes, 2015
One key issue when conceiving the body as a multisensory object is how the cognitive system integrates visible instances of the self and other bodies with one\u2019s own somatosensory processing, to achieve self-recognition and body ownership.
F., Pavani, Galfano, Giovanni
core   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Manipulation of phasic arousal by auditory cues is associated with subsequent changes in visual orienting to faces in infancy

open access: yesScientific Reports, 2023
This eye-tracking study investigated the effect of sound-induced arousal on social orienting under different auditory cue conditions in 5-month-old (n = 25; n = 13 males) and 10-month-old infants (n = 21; n = 14 males) participating in a spontaneous ...
Giorgia Bussu   +4 more
doaj   +1 more source

The orienting mouse: An input device with attitude [PDF]

open access: yes, 2013
This paper presents a modified computer mouse, the Orienting Mouse, which delivers orientation as an additional dimension of input; when the mouse is moved on a flat surface it reports, in addition to the conventional x, y translation, angular rotation ...
Apperley, Mark, Rogers, Bill
core   +1 more source

The double of the doubles of Klein surfaces [PDF]

open access: yes, 2015
A Klein surface is a surface with a dianalytic structure. A double of a Klein surface $X$ is a Klein surface $Y$ such that there is a degree two morphism (of Klein surfaces) $Y\rightarrow X$. There are many doubles of a given Klein surface and among them
Costa, Antonio F.   +2 more
core   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

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