Results 51 to 60 of about 205,980 (312)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Representational coding of overt and covert orienting of visuospatial attention in the frontoparietal network

NeuroImage, 2022
Orienting of visuospatial attention refers to reallocation of attentional focus from one target or location to another and can occur either with (overt) or without (covert) eye movement.
Tingting Wu, Melissa-Ann Mackie, Chao Chen, Jin Fan   +3 more
doaj   +1 more source

Nonmagnetic, explosive actuated indexing device Patent [PDF]

, 1967
Development of non-magnetic indexing device for orienting magnetic flux sensing instrument in magnetic field without generation of detrimental magnetic ...
Bauernschub, J. P., Jr.
core   +1 more source

Hydrodynamic orienting of asymmetric microobjects under gravity

, 2008
It is shown that nonsymmetric microobjects orient while settling under gravity in a viscous fluid. To analyze this process, a simple shape is chosen: a non-deformable `chain'. The chain consists of two straight arms, made of touching solid spheres.
Childress S, Ekiel-Jeżewska M L, Eligiusz Wajnryb, Happel J, Kim S, Maria L Ekiel-Jeżewska, Press W H   +6 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Orienting Transversals and Transition Polynomials of Multimatroids

, 2017
Multimatroids generalize matroids, delta-matroids, and isotropic systems, and transition polynomials of multimatroids subsume various polynomials for these latter combinatorial structures, such as the interlace polynomial and the Tutte-Martin polynomial.
Brijder, Robert
core   +1 more source

The neural correlates of social attention: automatic orienting to social and nonsocial cues [PDF]

, 2009
Previous evidence suggests that directional social cues (e.g., eye gaze) cause automatic shifts in attention toward gaze direction. It has been proposed that automatic attentional orienting driven by social cues (social orienting) involves a different ...
Deanna J. Greene, Eric Mooshagian, Jonas T. Kaplan, Eran Zaidel, Marco Iacoboni, MS Beauchamp, M Corbetta, M Corbetta, M Corbetta, JC Culham, B de Haan, MC Dorris, J Driver, NJ Emery, CK Friesen, CK Friesen, CK Friesen, A Frischen, I Gauthier, MH Grosbras, T Haarmeier, JV Haxby, JK Hietanen, EA Hoffman, CI Hooker, M Jenkinson, M Jenkinson, J Jonides, N Kanwisher, YH Kim, A Kingstone, A Kingstone, A Kingstone, R Klein, RJ Krauzlis, SR Langton, AR Mayer, D McKee, MM Mesulam, MM Mesulam, MW Mosconi, NG Muller, AC Nobre, H Noda, RC Oldfield, T Paus, KA Pelphrey, DI Perrett, MI Posner, RD Rafal, J Ristic, G Rizzolatti, FR Robinson, AC Rosen, A Sapir, CM Tipper, J Tipples, TD Wager, MG Woldorff, KJ Worsley   +59 more
core   +2 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Electroencephalography (EEG)-Derived Markers to Measure Components of Attention Processing [PDF]

, 2017
Although extensively studied for decades, attention system remains an interesting challenge in neuroscience field. The Attention Network Task (ANT) has been developed to provide a measure of the efficiency for the three attention components ...
Anzolin, Alessandra, Astolfi, Laura, Cincotti, Febo, Mattia, Donatella, Pichiorri, Floriana, Riccio, Angela, Toppi, Jlenia   +6 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source