Results 201 to 210 of about 1,845,192 (267)

Coronary Artery Origin Anomalies on Coronary CT Angiography: A Single-Center Tertiary-Care Cohort. [PDF]

J Clin Pract Res
Karatoprak NB, Karatoprak S, Şahin Ö.
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Challenging the prokaryotic MGE-defense origin of eukaryotic RNA editing. [PDF]

mLife
Duan Y, Xie Q, Yang J, Cai W, Li H.
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Self-Reference and Atrial Pace Mapping With iPASO Identify Multiple Non-Pulmonary vein Triggers in Atrial Fibrillation. [PDF]

JACC Case Rep
Kato Y, Sagawa Y, Murata K, Arai H, Oda A, Kishaba J, Yasui Y, Kouguchi T, Arima H, Yamauchi Y.   +9 more
europepmc   +1 more source

High-takeoff anomalous right coronary artery arising from the ascending aorta: a case report. [PDF]

BMC Cardiovasc Disord
Raj PJA, Sundaramurthy A, Parthasarathy H.   +2 more
europepmc   +1 more source

Can cumulative disadvantages be reversed? Class attainment and a network analysis of intergenerational occupational pathways by migratory origin in Buenos Aires, Argentina. [PDF]

Front Sociol
Dalle P, Carrascosa J.
europepmc   +1 more source