Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Author Correction: Task-dependent representations of stimulus and choice in mouse parietal cortex. [PDF]
In the original version of this Article, the Acknowledgements section was inadvertently omitted.
Crawford, Benjamin +4 more
core +3 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Anatomy of original research article and reporting checklists
Writing a manuscript requires a lot of time and skill. The manuscript structure and reporting checklists play an important role for authors to complete the manuscript in a timely manner.
M V Sruthi
doaj +1 more source
Original article Unfulfilled parenthood in the eyes of young adults
Background The goal of the study was to present young adults’ perceptions of the experience of loss of a child at different stages of its prenatal development, as well as the level of declared support for couples after the loss.
Alicja Kalus, Ewa Kiełek-Rataj
doaj +1 more source
Addendum to Informatics for Health 2017: Advancing both science and practice [PDF]
This article presents presentation and poster abstracts that were mistakenly omitted from the original ...
Cornet, Ronald +3 more
core +4 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
ORIGINAL ARTICLE: A New Embalming Fluid for Preserving Cadavers [PDF]
Background: Dissection laboratory is the only place where the three dimensional structure of the human body is reinforced by visual, auditory and tactile pathways.
P.E. Natekar, F. M. Desouza
doaj
Correction to: Ten years malaria trend at Arjo-Didessa sugar development site and its vicinity, Southwest Ethiopia: a retrospective study. [PDF]
Following publication of the original article [1], it came to the authors' attention that unfortunately the last name of one of the authors is spelled incorrectly in the published ...
Demissew, Assalif +8 more
core +2 more sources
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source

