Results 51 to 60 of about 79,683,097 (270)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Quality of Published medical articles in approved Medical Journals by Islamic Republic of Iran Committee of Medical Journal (1983-2005)

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2010
Background and Objective: Quality of medical articles is effective at improvement of medical science. This study was done for determining of published medical articles quality in approved Medical Journals.
Alaedini F(PhD)   +5 more
doaj  

Characterisation of Maclura cochinchinensis (Lour.) Corner Trunk Heartwood Extract and its Toxicity Evaluation

open access: yesJournal of Pharmacy
Introduction:  Maclura cochinchinensis is widely used as a natural dye for clothing in Indonesia. Besides, there are some researches about its activities as an antioxidant, antimicrobial, and antidiabetic.
Esti Mumpuni   +3 more
doaj   +1 more source

ORIGINAL ARTICLE: A New Embalming Fluid for Preserving Cadavers [PDF]

open access: yesJournal of Krishna Institute of Medical Sciences University, 2012
Background: Dissection laboratory is the only place where the three dimensional structure of the human body is reinforced by visual, auditory and tactile pathways.
P.E. Natekar, F. M. Desouza
doaj  

Original article

open access: yesNutrición Clínica y Dietética Hospitalaria
Introduction: Iron deficiency anemia (IDA) is a highly prevalent nutritional deficiency among children worldwide, primarily driven by inadequate iron intake. Iron intake is influenced by a household’s ability to access food and the diversity of foods consumed.
Iseu Siti Aisyah   +5 more
openaire   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Original article Entitlement and subjective well-being: a three-nations study

open access: yesHealth Psychology Report, 2015
Background The current study investigated the role of three facets of entitlement (active, passive and revenge) in various forms of subjective well-being (SWB): hedonistic and two facets of eudaimonic well-being (social and psychological).
Magdalena Żemojtel-Piotrowska   +5 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

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