Results 61 to 70 of about 79,683,097 (270)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Eurasian Journal of Emergency Medicine, 2016 Aim: Bibliographic work in the Turkish emergency medicine community is very scarce. We aim to improve upon the shortcomings in this area.Materials and Methods: Original research published in the Eurasian Journal of Emergency Medicine (EAJEM) (formerly ...
Mücahit Emet +4 more
doaj +1 more source
Original article Unfulfilled parenthood in the eyes of young adults
Health Psychology Report, 2014 Background The goal of the study was to present young adults’ perceptions of the experience of loss of a child at different stages of its prenatal development, as well as the level of declared support for couples after the loss.
Alicja Kalus, Ewa Kiełek-Rataj
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Original article Psychological determinants of portfolio workers’ satisfaction with life
Health Psychology Report, 2014 Background The objective of the study was to evaluate which psychological variables are determinants of the level of satisfaction with life in the case of workers employed in more than one workplace, called portfolio workers.
Agnieszka Lipińska-Grobelny
doaj +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Addison's Disease: Evaluation of Twenty Nine Cases - Original Article
Endocrinology Research and Practice, 2006 Primary adrenal failure (Addison's disease) is a clinical disorder characterized by destruction of the adrenal cortex leading to decreased production of glucocorticoids, mineralocorticoids, and/or adrenal androgens.
Hulusi Atmaca +3 more
doaj +2 more sources
Original article Personality determinants of motivation to undertake vocational training
Current Issues in Personality Psychology, 2014 Background Recently, at a time of frequent changes in the economic and socio-economic circumstances, knowledge acquired in the course of formal education is insufficient.
Dorota Godlewska-Werner +3 more
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source