Results 61 to 70 of about 10,301,920 (247)
Original article Personality superfactors and healthy behaviors of professional athletes
Current Issues in Personality Psychology, 2014 Background Personality traits seem to be excellent predictors of starting, continuing and discontinuing physical activity. Moreover, they constitute an important determinant of health-seeking behaviors.
Mariusz Lipowski, Łucja Bieleninik
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Original article Portfolio working – a psychological analysis of the phenomenon
Current Issues in Personality Psychology, 2014 Background It turns out from the latest Eurostat data that Poland holds the second place in Europe in terms of the number of so-called portfolio workers, i.e. persons who work for more than one employer.
Agnieszka Lipińska-Grobelny
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Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Eurasian Journal of Emergency Medicine, 2016 Aim: Bibliographic work in the Turkish emergency medicine community is very scarce. We aim to improve upon the shortcomings in this area.Materials and Methods: Original research published in the Eurasian Journal of Emergency Medicine (EAJEM) (formerly ...
Mücahit Emet +4 more
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Addison's Disease: Evaluation of Twenty Nine Cases - Original Article
Endocrinology Research and Practice, 2006 Primary adrenal failure (Addison's disease) is a clinical disorder characterized by destruction of the adrenal cortex leading to decreased production of glucocorticoids, mineralocorticoids, and/or adrenal androgens.
Hulusi Atmaca +3 more
doaj +2 more sources
Original article Unfulfilled parenthood in the eyes of young adults
Health Psychology Report, 2014 Background The goal of the study was to present young adults’ perceptions of the experience of loss of a child at different stages of its prenatal development, as well as the level of declared support for couples after the loss.
Alicja Kalus, Ewa Kiełek-Rataj
doaj +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source