Results 101 to 110 of about 1,438,384 (168)

Microneedle-based transdermal delivery systems for metabolic bone diseases: advances, challenges, and future perspectives. [PDF]

open access: yesFront Bioeng Biotechnol
Xie X   +10 more
europepmc   +1 more source

The Origin of Antithyroid Drugs

Thyroid®, 2023
Background: When the antithyroid drugs were discovered in the early 1940s, they were immediately recognized as a revolutionary new treatment for hyperthyroidism. Although much has been learned about their mechanism of action and clinical utility, they continue to be used today in much the same way as they have been since their introduction. Summary: In
Clark T, Sawin, David S, Cooper
openaire   +3 more sources

Origins of Drug Molecules

2021
This chapter recounts how human ancestors chewed tree bark and drank herbal tea to relieve their illnesses, whereas today people are more likely to visit the doctor and take prescribed medication. Modern medication generally appears in tablet or capsule form, and the active ingredient will have first appeared in pure form on a chemist's bench.
openaire   +1 more source

Drug molecules of marine origin

1990
Somewhat accelerated developments in the chemistry and pharmacology of marine molecules during the eighties are a clear indication of the biomedical potential of marine organisms for the twenty-first century. Unfortunately, the overall effort toward the field is still insignificant.
openaire   +2 more sources

The origins of antimalarial drug resistance

Trends in Parasitology, 2004
Resistance of Plasmodium falciparum to the antimalarial drug sulfadoxine-pyrimethamine is a result of extremely rare mutations that have spread over large geographical areas. This pattern was completely unexpected because mutations encoding resistance occur commonly in laboratory conditions, leading to the expectation that resistance would originate ...
openaire   +2 more sources

The Origins of Antimalarial-Drug Resistance

New England Journal of Medicine, 2014
There is a tendency to view the development of antimalarial-drug resistance as an inevitable outcome of the drugs' widespread use. Yet resistance has been accelerated by the way the drugs are used and by the social and economic conditions in which they are used.
openaire   +2 more sources

The Origins of Drugs

2012
A brief history of the discovery and invention of a selection of drugs is provided as an introduction to this textbook on clinical trials. Examples were chosen from drugs that are classified as natural products, analogues of naturallyoccurring metabolites, antibodies, and drugs identified by screening libraries of chemicals. Also, as an introduction to
openaire   +1 more source

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