Results 101 to 110 of about 5,486,911 (302)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Correction to: Clinical diversity of invasive cryptococcosis in AIDS patients from central China: report of two cases with review of literature

open access: yesBMC Infectious Diseases, 2019
After publication of the original article [1], we were notified that Figs. 1 and 2 has been misplaced. Hence, the position of the two pictures should be reversed.
Yongxi Zhang   +4 more
doaj   +1 more source

Study on the consistency of the position of the brackets on the digital occlusal model and the actual position af⁃ ter indirect bonding

open access: yes口腔疾病防治, 2017
Objective To provide the experimental basis for the coherence of the indirect bond position by compar⁃ ing the position of the bracket on the digital occlusal model and the position of the transfer to the initial plaster model.
BAO Li ⁃ na
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Slovosled posesivních zájmen ve staré češtině

open access: yesLinguistica Brunensia, 2014
The primary aim of this paper is to compare the word order of possessive pronouns in the noun phrase in Modern Czech and Old Czech. The attention is devoted especially to the type of possessive pronouns, rhythmic articulation, topic and focus phrase, etc.
Olga Navrátilová
doaj  

Study of the Similarities in Scale Models of a Single-Layer Spherical Lattice Shell Structure under the Effect of Internal Explosion

open access: yesShock and Vibration, 2017
The similarity of each scale model is verified based on the theory of similarity, deriving the similarity law of internal explosions in a single-layer spherical lattice shell structure via dimensional theory, calculated based on models with scaling ...
Wenbao Wang, Xuanneng Gao, Lihui Le
doaj   +1 more source

A new application of emulsions to measure the gravitational force on antihydrogen

open access: yes, 2012
We propose to build and operate a detector based on the emulsion film technology for the measurement of the gravitational acceleration on antimatter, to be performed by the AEgIS experiment (AD6) at CERN. The goal of AEgIS is to test the weak equivalence
Amsler, C.   +11 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Gordon Craig’s Scene Project: a history open to revision

open access: yesRevista Brasileira de Estudos da Presença, 2014
The article proposes a review of Gordon Craig’s Scene project, an invention patented in 1910 and developed until 1922. Craig himself kept an ambiguous position whether it was an unfulfilled project or not.
Luiz Fernando Ramos (University of São Paulo, São Paulo/SP, Brazil)
doaj   +2 more sources

A Study on Water Modeling Simulation for Slag Entrapment in 100 t Ladle with Bottom Argon Blowing during LF Refining Process

open access: yesTeshugang, 2014
According to the prototype of a 100 t ladle at steelworks and based on geometric similarity principle, a water model with model and prototype ratio 1:3.5 is established.
田罗林   +5 more
doaj  

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