Results 81 to 90 of about 5,511,969 (335)

IVOA Recommendation: Simple Cone Search Version 1.03

open access: yes, 2011
This specification defines a simple query protocol for retrieving records from a catalog of astronomical sources. The query describes sky position and an angular distance, defining a cone on the sky.
Hanisch, Robert   +3 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Analysis of Original Position Statistic Distribution on Solidification Segregation of Cast Billet

open access: yesTeshugang, 2007
The macrosegregation law  of  C,S,P  and  Al  in  240  mm×240  mm  cast  billet  of  steel  40Cr(0.38  ~ 0.40C,0.90~0.91Cr,0.015~0.029P,0.009~0.014S)has    been    studied    by  the    technology    of   original    position statistic  distribution ...
薛正良   +6 more
doaj  

The fallibility objection to the original position [PDF]

open access: yes
Do individuals in John Rawls’s original position take into account the fallibility of human nature? Some notable commentators on Rawls say that they do or that they should.
Edward, Terence Rajivan
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

The State of Nature, the Original Position and the Problem of historical Memory

open access: yesAnales del Seminario de Historia de la Filosofía, 2007
The comparison between the concept state of nature, as it appears in the contractualist theories of XVII and XVIII centuries, and the original position of the the- ory of justice by John Rawls, reveals the assumptions, difficulties and limitations of the
Francisco Castilla Urbano
doaj  

Image Reconstruction from Bag-of-Visual-Words

open access: yes, 2015
The objective of this work is to reconstruct an original image from Bag-of-Visual-Words (BoVW). Image reconstruction from features can be a means of identifying the characteristics of features.
Harada, Tatsuya, Kato, Hiroharu
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

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