Results 71 to 80 of about 5,511,969 (335)

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Multimedia Cryptography based on Liu and Chen Systems

open access: yesDiyala Journal of Engineering Sciences, 2016
Information security is an important matter in communication systems such as internet communication, multimedia systems, medical imaging, and especially military communication.
Hussien Y. Radhi
doaj   +1 more source

In Defense of Weak Scientism: A Reply to Brown [PDF]

open access: yes, 2017
In “What’s So Bad about Scientism?” (Mizrahi 2017), I argue that Weak Scientism, the view that “Of all the knowledge we have, scientific knowledge is the best knowledge” (Mizrahi 2017, 354; emphasis in original) is a defensible position.
Mizrahi, Moti
core  

Single and dual fiber nano-tip optical tweezers: trapping and analysis

open access: yes, 2013
An original optical tweezers using one or two chemically etched fiber nano-tips is developed. We demonstrate optical trapping of 1 micrometer polystyrene spheres at optical powers down to 2 mW.
Decombe, Jean-Baptiste   +2 more
core   +4 more sources

The Cliffordian Virtue [PDF]

open access: yes, 2013
There is a case to be made for the contention that it is a virtue to have a disposition to try to conform to W. K. Clifford’s ethics of belief. The arguments are not Clifford’s own but new deductive ones.
Zamulinski, Brian
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

The sensory origins of human position sense [PDF]

open access: yesThe Journal of Physiology, 2016
Key points Position sense at the human forearm can be measured in blindfolded subjects by matching positions of the arms or by a subject pointing to the perceived position of an unseen arm. Effects on position sense tested were: elbow muscle conditioning with a voluntary contraction, muscle vibration, loading the arm and elbow skin stretch ...
A J, Tsay   +3 more
openaire   +2 more sources

Revisiting Weyl's calculation of the gravitational pull in Bach's two-body solution [PDF]

open access: yes, 2001
When the mass of one of the two bodies tends to zero, Weyl's definition of the gravitational force in an axially symmetric, static two-body solution can be given an invariant formulation in terms of a force four-vector.
Abrams L S   +20 more
core   +4 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

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