Results 51 to 60 of about 6,189,902 (243)

Nationalism and the original position [PDF]

open access: yes
This is a one-page handout presenting some objections nationalists might or do make to John Rawls's original position ...
Edward, Terence Rajivan
core   +2 more sources

Biomechanical Evidence on Anterior Cruciate Ligament Reconstruction

open access: yesRevista Brasileira de Ortopedia
Objective Anterior cruciate ligament (ACL) reconstruction is recommended in athletes with high physical demands. Several techniques are used in reconstruction; however, themost relevant question still is the best biomechanical positioning for the graft.
António Completo   +3 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Spectral characterisation of nk pulse position modulation format [PDF]

open access: yes, 2005
nk pulse position modulation (PPM) is a new modulation format that has recently been proposed for the optical wireless channel. This Letter considers, for the first time, a full spectral characterisation of -PPM and presents original expressions, which
Cryan, R.A., Menon, M.
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

nk-pulse position modulation for optical wireless communication [PDF]

open access: yes, 2005
An original analysis is presented for nk-PPM in which the information is conveyed by the position of k pulses, each within their own frame of n-slots, giving nk-PPM symbols.
Cryan, R.A.   +3 more
core   +1 more source

Analysis of Original Position Statistic Distribution on Solidification Segregation of Cast Billet

open access: yesTeshugang, 2007
The macrosegregation law  of  C,S,P  and  Al  in  240  mm×240  mm  cast  billet  of  steel  40Cr(0.38  ~ 0.40C,0.90~0.91Cr,0.015~0.029P,0.009~0.014S)has    been    studied    by  the    technology    of   original    position statistic  distribution ...
薛正良   +6 more
doaj  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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