Results 111 to 120 of about 92,782 (337)
We are born into Original Sin and are by nature sinful and unclean.https://scholar.csl.edu/christiandoctrine/1025/thumbnail ...
Biermann, Joel
core
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Edwards (Jonathan) Original Sin
Séguy Jean. Edwards (Jonathan) Original Sin. In: Archives de sociologie des religions, n°31, 1971.
Séguy, Jean
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Original Antigenic Sin Shapes the Immunological Repertoire Evoked by Human Cytomegalovirus Glycoprotein B/MF59 Vaccine in Seropositive Recipients [PDF]
Ilona Baraniak +4 more
openalex +1 more source
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Is Dollarization the Right Option? Financial Fragility, Original Sin and Fear of Floating [PDF]
This paper focuses on the option of dollarization or euroization for emerging-market economies. There are no “one-size-fits-all” exchange-rate policies for emerging- -market economies; however, there are macroeconomic disadvantages associated with ...
Roman Horváth
core
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
We investigate whether the fact that most countries cannot borrow internationally in their own currencies, referred to as "original sin" by Eichengreen and Hausmann (1999), may remain as a "mystery" when an alternative variable set ...
core
Retrieving Zwingli’s doctrine of original sin
Huldrych Zwingli’s understanding of original sin is usually sidelined in contemporary Reformed theology. In this paper I argue that Zwingli’s views are worthy of theological retrieval for contemporary dogmatics.
Crisp, Oliver D.
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source

