Results 51 to 60 of about 92,782 (337)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Local Currency Bond Markets [PDF]
This paper analyzes the development of 49 local bond markets. The main finding is that policies and laws matter: countries with stable inflation rates and strong creditor rights have more developed local bond markets and rely less on foreigncurrency ...
Francis E. Warnock, John D. Burger
core +2 more sources
Meta-Analysis of Human Nature through the Comparative Comparison of Judgmental Concepts in the Thought of Allameh Tabatabai and Augustine [PDF]
پژوهشنامه کلام تطبیقی شیعهHuman nature is one of the most important propositions of belief, which has become the starting point of contemporary insights about man, and it will be influential in the context of any school of thought that is translated.
Mohammad Esmaeil Abdollahi
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The Formation of the Teaching on Original Sin from the First Through the Fifth Centuries
Богословські роздуми: Східноєвропейський журнал богословʼя, 2016 This article surveys the sources, appearance, development, and establishment of the teaching on original sin as dogma. The material is presented in historical sequence and encompasses the period from the first to the fifth centuries when the church’s ...
Oleg BUDAKOV
doaj
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Original Sin, Preterition, and its Implications for Evangelization
Perichoresis: The Theological Journal of Emanuel University, 2020 In this paper, I examine the four elements—universal sinfulness, natural sinfulness, inherited sinfulness, and Adamic sinfulness—of the doctrine of original sin in both the Reformed confessions, with particular attention to the Canons of Dort, and the ...
Echeverria Eduardo J.
doaj +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source