Results 71 to 80 of about 2,161,493 (288)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
What is invariant? On the possibility and perspectives of the evolutionary theology
Studia Koszalińsko-Kołobrzeskie, 2018 The evolutionary theology is a new branch of theology in which the dynamic picture of the origin and development of life in Universe by means of the adaptive processes governed by the natural selection is considered to be the adequate ontological ...
Wojciech Grygiel
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Reply to Comment on `Ratchet universality in the presence of thermal noise'
, 2013 The Comment by Quintero et al (arXiv:1309.1065[nlin.PS])does not dispute the central result of our paper [Phys. Rev. E {87}, 062114 (2013)] which is a theory explaining the interplay between thermal noise and symmetry breaking in the ratchet transport of
Chacón, Ricardo, Martínez, Pedro J.
core +1 more source
BIOLOGICAL PERSPECTIVES ON FALL AND ORIGINAL SIN
Zygon, 1993 . The paper consists of an argument that goes as follows. Symbols and their elaboration into myths constitute Homo sapiens's most primitive reading of the world and the relation of humans to that world.
doaj +2 more sources
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Sequence Space Localization in the Immune System Response to Vaccination and Disease
, 2003 We introduce a model of protein evolution to explain limitations in the immune system response to vaccination and disease. The phenomenon of original antigenic sin, wherein vaccination creates memory sequences that can \emph{increase} susceptibility to ...
Deem, Michael W., Lee, Ha Youn
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Good Housekeeping? Reputation, Fixed Exchange Rates, and the 'Original Sin' Problem [PDF]
This paper examines how the choice of exchange rate regime can signal financial rectitude and, in so doing, influcence a country's ability to borrow internationally in domestic currency.
Kang Yong Tan, Prasanna Gai
core
An Investigation of Feral Children and Original Sin [PDF]
, 2010 In lieu of an abstract, below is the essay\u27s first paragraph. The subject of feral children has often been explored from a variety of viewpoints and angles.
Regelsberger, Christina
core +1 more source