Results 71 to 80 of about 92,782 (337)

Sudden Stops, Financial Crises, and Original Sin in Emerging Countries: Déjà vu? [PDF]

open access: yes
The current pattern of sudden stops and financial crises in emerging markets has great resonance to events in the first era of globalization, from 1870-1913.
Michael D. Bordo
core  

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

BIOLOGICAL PERSPECTIVES ON FALL AND ORIGINAL SIN

open access: yesZygon, 1993
. The paper consists of an argument that goes as follows. Symbols and their elaboration into myths constitute Homo sapiens's most primitive reading of the world and the relation of humans to that world.
doaj   +2 more sources

What is invariant? On the possibility and perspectives of the evolutionary theology

open access: yesStudia Koszalińsko-Kołobrzeskie, 2018
The evolutionary theology is a new branch of theology in which the dynamic picture of the origin and development of life in Universe by means of the adaptive processes governed by the natural selection is considered to be the adequate ontological ...
Wojciech Grygiel
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

The Original Sin of Writing and Reading

open access: yesReligions
This study examines the possible points of connection between crime and reading on the basis of genre-typical roles and motifs in detective fiction. I aim to identify characteristic reading methods, strategies, locations, events, and professions with ...
Kristián Benyovszky
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Current Account Deficits, Macroeconomic Policy Stance and Governance: An Empirical Investigation [PDF]

open access: yes
This paper empirically investigates the effects of institutional and macroeconomic policy stance variables on current account deficits (CAD). Based on cross-section data for a broad number of developing and industrial countries, the results strongly ...
Erdal Özmen
core  

Original Sin: A Flawed Inheritance [PDF]

open access: yes, 2000
The doctrine of original sin has left its negative mark not only on theology, but according to Nietzsche, on Western civilisation as a whole. Augustine generally takes the blame for this sombre tradition, not least because of his association of ...
Henry, Martin
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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