Results 51 to 60 of about 3,578 (249)
On the Origin of Interoception [PDF]
Frontiers in Psychology, 2016 Over the course of a century, the meaning of interoception has changed from the restrictive to the inclusive. In its inclusive sense, it bears relevance to every individual via its link to emotion, decision making, time-perception, health, pain, and various other areas of life. While the label for the perception of the body state changes over time, the
Ceunen, Erik +2 more
openaire +4 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The Failed Promise of Originalism /
, 2021 Originalism is an enormously popular-and equally criticized-theory of constitutional interpretation. As Elena Kagan stated at her confirmation hearing, "We are all originalists." Scores of articles have been written on whether the Court should use ...
Cross, Frank,
core +1 more source
Non-Originalism Differently: the Obligation of the Legislator to Respond to Changing Conditions
Przegląd Prawniczy Uniwersytetu im. Adama Mickiewicza, 2018 The question that the paper seeks to answer is formulated through reflections on the is-sues of non-originalism. Non-originalism refers to an approach to the interpretation of the Constitution where the text of the Constitution adapts to new conditions ...
Jana Kokešová
doaj +1 more source
Journal of Theoretical Biology, 2009 We study the origin of evolution. Evolution is based on replication, mutation, and selection. But how does evolution begin? When do chemical kinetics turn into evolutionary dynamics? We propose "prelife" and "prevolution" as the logical precursors of life and evolution. Prelife generates sequences of variable length.
Manapat, Michael L. +3 more
openaire +5 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
, 2016 If our law requires originalism in constitutional interpretation, then that would be a good reason to be an originalist. This insight animates what many have begun to call the “positive turn” in originalism.
Pojanowski, Jeffrey +3 more
core +1 more source
BALKIN, Jack M.: Living originalism
Časopis pro Právní Vědu a Praxi, 2015 Recenze publikace - BALKIN, Jack M.: Living originalism London, Cambridge, 2011, 474 s.
Michal Malaník
doaj
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Why Constitutional Meaning is not Necessarily Fixed - A Reply to Solum
Problema: Anuario de Filosofía y Teoría del Derecho, 2017 : In this paper, I show that certain parts of constitutional texts can plausibly be thought of as having a meaning that changes and evolves on its own. This idea is widely rejected, especially but not only by a group of legal theorists who subscribe to a
Katharina Stevens
doaj +1 more source