Results 31 to 40 of about 284,500 (247)
Retour sur les origines de la vie [PDF]
médecine/sciences, 2018 Regarder plus de trois milliards d’années en arrière est difficile et la reconstruction d’arbres de l’évolution à partir de l’ADN actuel repose sur des hypothèses cachées qui ne permettent pas de retrouver ses vraies racines. Cherchant à s’affranchir de notre anthropocentrisme, le scénario proposé dans les deux textes qui seront successivement publiés ...
openaire +4 more sources
L’essor de l’exobiologie planétaire dans le système solaire
Cahiers François Viète, 2003 The development of space exploration has opened the way to new research perspectives in the field of the origins of life (on Earth or elsewhere). Detailed in situ observation of other bodies in the solar system makes it possible to compare chemical and ...
François Raulin
doaj +1 more source
Du papyrus au parchemin: Les origines médiévales de la mémoire archivistique en Europe occidentale
Annales: Histoire, Sciences Sociales, 2019 Résumés Cet article cherche à reconstruire la transition du papyrus vers le parchemin dans les pratiques documentaires en Europe occidentale, afin de mieux comprendre les lacunes documentaires du haut Moyen Âge et, par conséquent, d’expliquer les ...
Dário Internullo
semanticscholar +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
DECLINAISONS IDENTITAIRES EN RÉCITS DE VIE
Fórum LinguísticoLe thème des "déclinaisons identitaires dans les récits de vie explore la manière dont les individus construisent et expriment leur identité à travers les récits personnels.
Martine Lani-Bayle +1 more
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Cahiers d’Études Romanes, 1998 Il Prato in fondo al mare, de Stanislao Nievo, est à la fois le roman d’un naufrage et le naufrage de plusieurs romans possibles. Reprenant l’enquête sur la mystérieuse disparition du navire qui ramenait son arrière grand-père Ippolito, de Palerme à ...
Marie-Anne Rubat du Mérac
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source