Results 61 to 70 of about 284,500 (247)

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar, Jeremy Johnson, Susanne Watkins, Eoin Mulroy   +3 more
wiley   +1 more source

H.L.A. Hart et J. Glover : un point de vue utilitariste contre la peine de mort

Canadian Journal of Bioethics, 2019
Dans cet article, je reviens sur les origines du chapitre sur la peine de mort de Questions de vie ou de mort de J. Glover, à savoir un article de 1957 de Hart, Murder and the Principles of Punishment : England and the United States.
Nicolas Nayfeld
doaj   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

Exil, diaspora et migrations dans "En attendant la montée des eaux", de Maryse Condé

Revista Criação & Crítica, 2022
Roman choral à l’intérieur duquel s’effectuent de nombreux allers-retours entre passé et présent, En attendant la montée des eaux de Maryse Condé raconte le destin de trois hommes – Babakar, Fouad et Movar – en errance, unis par une petite orpheline ...
Mathilde Berg
doaj  

Le heritage-scape : origines, éléments théoriques et examen critique d’un modèle de compréhension du Programme du patrimoine mondial de l’UNESCO

Via@, 2018
L’auteur de The Heritage-scape : UNESCO, World Heritage and Tourism (Lexington 2009), développe dans cet article une réflexion critique sur le concept de heritage-scape, introduit dans la littérature il y a presque dix ans.
Michael A. Di Giovine
doaj   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif, Diane Demailly, Gabriella A. Horvàth, Juan Dario Ortigoza Escobar, Nathalie Dorison, Mayté Castro Jiménez, Cécile A. Hubsch, Thomas Wirth, Gun‐Marie Hariz, Sophie Huby, Morgan Dornadic, Zohra Souei, Muhammad Mushhood Ur Rehman, Simone Hemm, Mehdi Boulaymen, Eduardo M. Moraud, Jocelyne Bloch, Xavier Vasques   +17 more
wiley   +1 more source

Regards croisés des stagiaires et des élèves sur l’origine d’incidents disciplinaires significatifs au cours d’éducation physique

eJournal de la Recherche sur l'Intervention en Éducation Physique et Sport, 2008
La présence des incidents disciplinaires à l’école n’est pas récente. Ce qui est nouveau, c’est l’ampleur qu’a tendance à prendre cette réalité, au point de rendre la vie des enseignants fort difficile (Galand, 2004, Galand et al., 2004).
Philippe Dervaux, Ghislain Carlier, Philippe Gérard   +2 more
doaj   +1 more source

Risk of Retinopathy Associated with Long‐Term Use of Hydroxychloroquine in Patients with Rheumatic Diseases: A Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective We aimed to estimate the prevalence and cumulative incidence of hydroxychloroquine retinopathy (HCQ‐R) and its risk factors among patients receiving long‐term HCQ with rheumatic diseases through a systematic review and meta‐analysis of observational studies that used spectral‐domain optical coherence tomography (SD‐OCT) for screening ...
Narsis Daftarian, Chloe Yue, Steve D Levasseur, Hui Xie, J. Antonio Avina‐Zubieta   +4 more
wiley   +1 more source

A segregação dos jovens em Paris

Dados: Revista de Ciências Sociais, 2012
Parce que leur vie quotidienne est fortement inscrite dans leur quartier de résidence, la ségrégation urbaine a des conséquences plus particulièrement importantes pour les jeunes.
Edmond Préteceille
doaj   +1 more source