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Macromolecules and the Origin of Life

Origins of Life, 1974
From our knowledge of present day organisms, it is hard to imagine a living assembly, even at its most primitive stage, without macromolecules. In order to look for the macromolecules which possibly participated in the assembly of the primitive organisms, the reaction and formation of polymers in HCN under irradiation of ultraviolet ray of 184.9 nm ...
H, Noda, H, Mizutani, H, Okihana
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The origin of life in comets

International Journal of Astrobiology, 2007
AbstractMechanisms of interstellar panspermia have recently been identified whereby life, wherever it has originated, will disperse throughout the habitable zone of the Galaxy within a few billion years. This re-opens the question of where life originated.
W.M. Napier   +2 more
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The origins of research into the origins of life

Endeavour, 2006
Most scientists at the end of the 19th and the beginning of the 20th century chose to ignore the question of the origin of life on Earth, regarding it as too mysterious and complex to handle. Yet, in the early 1950s an experimental field devoted to the study of the problem made its first steps. The pioneering theories of several scientists in the first
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Hypercycles and the origin of life

Nature, 1979
Perhaps the most difficult step to explain in the origin of life is that from the replication of molecules (RNA for example) in the absence of specific proteins, to the appearance of polymerases and other proteins involved in the replication of RNA and themselves coded for by that RNA.
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Chance and the Origin of Life

Origins of Life, 1977
Random chemical reactions in the Earth's primitive hydrosphere could have generated no more than 200 bits of information, whereas the first Darwinian organism must have encoded about a million bits, and therefore could not have arisen by chance. This information gap is bridged by separating reproduction from organism, and postulating a reproductive ...
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On the origin of life on earth

Aids Reviews
The creation of the universe out of nothing (ex nihilo) is attributable to the eternal God. Would a direct divine intervention be needed for other singular events, such as the origin of life? Taking apart the human being, created to image and resemblance of God, we argue that current scientific knowledge allows us to rationally admit a continuity ...
Vicente, Soriano, Rubén, Herce
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On the origin of life event

Origins of life and evolution of the biosphere, 1988
On the assumption of a uniform sample space probability hypothesis it is estimated a maximum number of polypeptides (or other kind of polymers) that could be synthesized in the prebiotic Earth. Besides, on the basis of five premises that are postulated as indispensable requirements for the origin of a living system, under the constraints of a protein ...
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Clay and the origin of life

Origins of Life, 1982
Research concerning the possible role of clay in chemical evolution is reviewed. The probable importance of clays in the origin of life is assessed.
C, Ponnamperuma   +2 more
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Symbiosis and the origin of life

Origins of Life, 1977
The paper uses chemical kinetic arguments and illustrations by computer modelling to discuss the origin and evolution of life. Complex self-reproducing chemical systems cannot arise spontaneously, whereas simple auto-catalytic systems can, especially in an irradiated aqueous medium.
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Bioceramics and the origin of life

Journal of Biomedical Materials Research, 1989
AbstractCreation of life involves establishing an organism that is capable of self‐maintenance, self‐reproduction, and adjustment to a changing environment. A Bioactive Substrate Theory of the origin of life is proposed, where the function of the bioactive substrates was to achieve the irreversible ordering of macromolecules into replicative structures.
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