Results 271 to 280 of about 1,431,470 (343)

Simulating the origins of life: The dual role of RNA replicases as an obstacle to evolution. [PDF]

open access: yesPLoS One, 2017
Szostak N   +4 more
europepmc   +1 more source

The System View of the Origin of Cellular Life

open access: bronze, 2018
Pier Luigi Luisi   +99 more
openalex   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

L-form bacteria, chronic diseases and the origins of life. [PDF]

open access: yesPhilos Trans R Soc Lond B Biol Sci, 2016
Errington J   +3 more
europepmc   +1 more source

Family-of-origin aggression, dating aggression, and physiological stress reactivity in daily life

open access: green, 2019
Adela C. Timmons   +6 more
openalex   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

The SOL $\textit{(Solar Origin and Life)}$ Project: Detailed characterization of candidates for the ZAMS and Subgiant stages [PDF]

open access: green
C. Eduardo-Oliveira S.   +5 more
openalex  

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