Results 91 to 100 of about 12,566 (192)
Orlistat-associated adverse effects and drug interactions: a critical review
Orlistat, an anti-obesity drug, is a potent and specific inhibitor of intestinal lipases. In light of the recent US FDA approval of the over-the-counter sale of orlistat (60 mg three times daily), clinicians need to be aware that its use may be ...
Elisaf, M. S. +5 more
core
Treatment with phototherapy or with the lipase inhibitor orlistat decreases plasma unconjugated bilirubin (UCB) concentrations in hyperbilirubinemic Gunn rats.
Hafkamp, AM +15 more
core +1 more source
Evaluation of gut microbiota alterations following orlistat administration in obese mice
BackgroundThe gut microbiota plays a pivotal role in various metabolic disorders. Orlistat has shown beneficial effects on weight loss and metabolism, but its direct impact on the gut microbiota has not been extensively reported.
Chang Xue +5 more
doaj +1 more source
Effect of orlistat on cardiovascular disease risk in obese adults
Aim: The aim of this study is to compare the effect of orlistat vs. placebo on the predicted 10-year cardiovascular disease (CVD) risk in obese people with one or more cardiovascular risk factors treated for 12 months, in conjunction with a fat-reduced ...
J. Proietto +28 more
core +1 more source
Weight management and current options in pharmacotherapy: Orlistat and Sibutramine
BACKGROUND: Chronic obesity is associated with various cardiovascular disorders, including diabetes, dyslipidemia, and hypertension. Pharmacotherapy with antiobesity agents is an important management strategy in conjunction with lifestyle interventions ...
Thomas, Graham; id_orcid +3 more
core +1 more source
H, Chabrol, G, Péresson, S, Callahan
openaire +2 more sources
The pathophysiology of faecal spotting in obese subjects during treatment with orlistat.
BACKGROUND The intermittent loss of oil or liquid faeces ('spotting') is an adverse effect that occurs in obese patients during treatment with the lipase inhibitor orlistat; the pathophysiology is unknown.
Fox M +5 more
core +1 more source
Orlistat, a potent inhibitor of the pancreatic and intestinal lipases, is the first member of a new therapeutic class approved for the treatment of obesity.
Sternon, J., Crenier, Laurent
core
Introduction: The prevalence of obesity, a serious public health problem, is increasing among teenagers and thus also increases cardiovascular morbidity and mortality in adulthood.
E. García Díaz, T. Martín Folgueras
doaj
Changes in Plasma Leptin Levels in Men in Response to Aerobic Training, and Using Orlistat
Background: Obesity is a complex disorder with excessive accumulation of adipose tissue; the tissue that exudes leptin, a hormone which plays an important role in the regulation of cellular metabolism and energy balance.
Abazar Teimoori +3 more
doaj

