Results 31 to 40 of about 1,153 (98)
Aquaculture Research, Volume 2025, Issue 1, 2025.This systematic literature review and meta‐analysis synthesizes empirical findings regarding the application of vaccines against Streptococcus infections in tilapia culture. Beyond systematically assessing advances and future directions in anti‐Streptococcus vaccination, we examined vaccine effects on prechallenge immunomodulation and postchallenge ...
Abdulwakil Olawale Saba +6 more
wiley +1 more source
Quo vadis ureagenesis disorders? A journey from 90 years ago into the future
Journal of Inherited Metabolic Disease, Volume 47, Issue 6, Page 1120-1128, November 2024.Abstract The pathway of ammonia disposal in the mammalian organism has been described in 1932 as a metabolic cycle present in the liver in different compartments. In 1958, the first human disorder affecting this pathway was described as a genetic condition leading to cognitive impairment and constant abnormalities of amino acid metabolism.
Johannes Häberle +2 more
wiley +1 more source
Comparative analysis of gene and disease selection in genomic newborn screening studies
Journal of Inherited Metabolic Disease, Volume 47, Issue 5, Page 945-970, September 2024.Abstract Genomic newborn screening (gNBS) is on the horizon given the decreasing costs of sequencing and the advanced understanding of the impact of genetic variants on health and diseases. Key to ongoing gNBS pilot studies is the selection of target diseases and associated genes to be included.
Isabel R. Betzler +8 more
wiley +1 more source
An essential protease, FtsH, influences daptomycin resistance acquisition in Enterococcus faecalis
Molecular Microbiology, Volume 121, Issue 5, Page 1021-1038, May 2024.FtsH, a conserved protease, influences daptomycin resistance evolution rates in Enterococcus faecalis by indirectly affecting the availability of the chaperone repressor HrcA. FtsH is also essential in the wild‐type genetic background where its loss of function results in altered metabolism in terms of decreased extracellular acidification and ability ...
Zeus Jaren Nair +10 more
wiley +1 more source
Characterizing arginine, ornithine, and putrescine pathways in enteric pathobionts
MicrobiologyOpen, Volume 13, Issue 2, April 2024.The amino acid L‐arginine is converted by bacteria into a variety of downstream metabolites, including citrulline, agmatine, ornithine, putrescine, and gamma‐aminobutyric acid (GABA). Our study shows that both Gram‐negative bacteria (Escherichia coli, Klebsiella pneumoniae, Klebsiella aerogenes, Pseudomonas fluorescens, and Acinetobacter baumannii) and
Ian M. Lillie +5 more
wiley +1 more source
Advanced Science, Volume 11, Issue 12, March 27, 2024.This investigation delves into the role of Sirtuin 3 (SIRT3), a mitochondrial deacetylase, within endothelial cells during atherosclerosis. The findings elucidate that the deletion of endothelial SIRT3 induces hyperacetylation and inactivation of Argininosuccinate Synthase 1 (ASS1), thereby disrupting the crucial L‐arginine synthesis pathway.
Xiaoyun Cao +7 more
wiley +1 more source
Pedigree and Functional Analysis of Two Cryptic OTC Variants Causing Ornithine Transcarbamylase Deficiency in Two Unrelated Chinese Male Patients. [PDF]
Mol Genet Genomic MedWang Q +5 more
europepmc +1 more source
Fatal Late-Onset Ornithine Transcarbamylase Deficiency in an Adolescent: A Case Report. [PDF]
CureusChristou E +4 more
europepmc +1 more source
Clinical heterogeneity, genotype, and neurological outcomes in six Palestinian patients with ornithine transcarbamylase deficiency. [PDF]
BMC PediatrDweikat I +4 more
europepmc +1 more source