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Glutamate, Ornithine, Arginine, Proline, and Polyamine Metabolic Interactions: The Pathway Is Regulated at the Post-Transcriptional Level [PDF]

open access: yesFrontiers in Plant Science, 2016
The metabolism of glutamate into ornithine, arginine, proline, and polyamines is a major network of nitrogen-metabolizing pathways in plants, which also produces intermediates like nitric oxide, and γ-aminobutyric acid (GABA) that play critical roles in ...
Maegan A Gagne, Rakesh Minocha
exaly   +5 more sources
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Ornithine decarboxylase and ornithine decarboxylase‐inhibiting activity in rat thymocytes

Cell Biochemistry and Function, 1992
AbstractIsolation of thymocytes from rat thymus resulted in the disappearance of the high activity of ornithine decarboxylase (ODC) that characterizes the thymus of young rats, together with the appearance of an antizyme‐like ODC inhibiting activity, which showed a chromatographic profile that resembled that of dexamethasone‐treated rat thymus ...
C, Stefanelli   +4 more
openaire   +2 more sources

Stereochemistry of Ornithine Decarboxylase Reaction

The Journal of Biochemistry, 1984
To determine the steric course of the reaction of bacterial ornithine decarboxylase [EC 4.1.1.17], we have carried out the decarboxylation of L-ornithine in 2H2O and that of DL-[2-2H]ornithine in H2O, and obtained putrescine bearing a single deuterium atom in the C-1 position.
Y, Asada   +4 more
openaire   +2 more sources

Ornithine decarboxylase in Paracoccidioides brasiliensis

Archives of Microbiology, 1996
Ornithine decarboxylase in Paracoccidioides brasiliensis, a dimorphic human pathogenic fungus, was more active at 37 degrees C in the yeast phase and at 30 degrees C in the mycelial phase. In contrast to other fungal systems, yeast growth and mycelium-to-yeast transition in P.
G, San-Blas   +3 more
openaire   +2 more sources

Turnover of trypanosomal ornithine decarboxylases

Biochemical Society Transactions, 2003
Interestingly, there is a major difference in turnover rate between ornithine decarboxylases (ODCs) from various trypanosomatids. ODCs from Trypanosoma brucei and Leishmania donovani are both stable proteins, whereas ODC from Crithidia fasciculata is a metabolically unstable protein in the parasite. C.
L, Persson, A, Jeppsson, S, Nasizadeh
openaire   +2 more sources

In SituMicroassay of Ornithine Decarboxylase

Analytical Biochemistry, 1996
Ornithine decarboxylase catalyses the principal step in the biosynthesis of polyamines (1, 2) and is reported to be a proto-oncogen implicated in the control of both FIG. 1. Modified rubber stopper. cell growth and transformation (3). Its activity is induced by a number of agents such as amino acids, pharmaceuticals, hormones, and growth stimuli (4 ...
C, Lobo, I N, de Castro, F J, Alonso
openaire   +2 more sources

Studies on Ornithine Decarboxylase Antizyme

1988
Tissue levels of ornithine decarboxylase (ODC) are under negative feedback regulation by polyamines. Thus, exogenously added polyamines cause a rapid decrease of ODC activity. Recent studies in various laboratories have indicated that the rapid decay of ODC activity caused by polyamines is due both to suppression of ODC synthesis (1–3) and to ...
S, Hayashi   +5 more
openaire   +2 more sources

A radiometric microassay for ornithine decarboxylase

Neuroscience, 1978
Abstract A simple method for purifying [ 3 H] l -ornithine and incubation conditions suitable for estimating l -ornithine decarboxylase activity are described. Routine and recycled cation exchange procedures for separating putrescine from ornithine are outlined. Blanks using the routine cation exchange method average approx.
J L, Maderdrut, R W, Oppenheim
openaire   +2 more sources

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