Results 71 to 80 of about 51,297 (232)
MedComm, Volume 7, Issue 11, November 2026.This comprehensive review summarizes gastric cancer epidemiology, multifactorial risk factors (like infectious, dietary, genetic), pathogenesis such as precancerous evolution, molecular alterations, and a focus on the bidirectional interactions between gastric cancer cells and macrophages in the tumor microenvironment.
Yixuan Xin +6 more
wiley +1 more source
The dual genetic control of ornithine transcarbamylase synthesis in Escherichia coli K12 [PDF]
, 1967 Mutations at 2 distant genes influence ornithine transcarbamylase synthesis in Escherichia coli K12. The wild type alleles of either of them restores to an OTC-less strain the ability to synthesize this enzyme under feedback control by ...
Sand, G. +5 more
core
, 2009 A 7-year-old female patient with a new diagnosis of ornithine transcarbamylase deficiency was treated for hyperammonemia with a standard protocol. Several days later, she developed ataxia, dysmetria, and dysarthria.
Bodensteiner, John B. +1 more
core +1 more source
Clinical and genetic analysis of five Chinese patients with urea cycle disorders
Molecular Genetics & Genomic Medicine, 2020 Background The urea cycle plays a key role in preventing the accumulation of toxic nitrogenous waste products, including two essential enzymes: ornithine transcarbamylase (OTC) and argininosuccinate lyase (ASL).
Zhenzhu Zheng +6 more
doaj +1 more source
, 1992 Zinc deficiency is common in cirrhosis and may be involved in the alteration of ammonia metabolism. Rats with carbon tetrachloride-induced cirrhosis have high plasma ammonia and low serum and tissue zinc levels.
Renzo Moretti +12 more
core +1 more source
Prenatal diagnosis of ornithine transcarbamylase deficiency: optimizing pregnancy outcome in a woman with previous affected babies [PDF]
, 2018 Ornithine Transcarbamylase (OTC) deficiency is an inherited X-linked disorder which predominantly affects males. Females are usually carriers and may rarely be symptomatic. Affected individuals may present with severe life threatening disease immediately
Chandrasekaran, Swaramya +3 more
core +1 more source
Immunological Characterization of Plant Ornithine Transcarbamylases [PDF]
Plant Physiology, 1990 Pea (Pisum sativum L.) ornithine transcarbamylase (OTC) antisera were used to investigate the immunological relatedness of several plant and animal OTC enzymes. The antisera immunoprecipitated OTC activity in all monocot and dicot species tested, and sodium dodecyl sulfate polyacrylamide gel electrophoresis analysis of immunoprecipitated protein ...
R D, Slocum +3 more
openaire +2 more sources
Journal of Medical Case Reports, 2018 Background Sodium valproate is a commonly used anticonvulsant. It is widely recognized that valproate can cause hyperammonemia, particularly in people with underlying liver disease.
Shaine Mehta +2 more
doaj +1 more source
Health Science Reports, Volume 9, Issue 10, October 2026.ABSTRACT Background and Aim Maple Syrup Urine Disease (MSUD) is a metabolic disorder affecting branched‐chain amino acid metabolism. While neurological symptoms are well‐characterized, cutaneous manifestations such as acrodermatitis dysmetabolica (AD) caused by isoleucine deficiency remain underrecognized.
Bahareh Abtahi‐naeini +4 more
wiley +1 more source
Mutation of ornithine transcarbamylase (H136R) in a girl with severe intermittent orotic aciduria but normal enzyme activity [PDF]
, 2018 Ornithine transcarbamylase deficiency shows X-linked inheritance with partial dominant expression in carrier females. We studied a girl with intermittent severe orotic aciduria and mild hyperammonaemia despite apparently normal enzyme activity in the ...
Wermuth, B. +6 more
core