Microtopography enhances intestinal drug absorption via Piezo1‐mediated tight junction modulation
BMEMat, EarlyView.Microtopography‐driven enhancement of oral peptide drug delivery by activating Piezo1 channels significantly improves paracellular permeability and bioavailability, offering a novel approach for optimizing macromolecule absorption in pharmaceutical formulations.
Yu Hu +12 more
wiley +1 more source
Stage T4B head and neck cancer survival outcome comparisons based on treatment modality: is surgery a viable treatment option? [PDF]
, 2016 IMPORTANCE: Advanced stage head and neck cancers are often deemed unresectable due to the aggressive nature of the cancer. In evaluating survival patterns of patients with stage IVb tumors, it is valuable to determine whether patients who undergo ...
Kidwai, Neiha
core +1 more source
Variations in concerns reported on the Patient Concerns Inventory (PCI) in head and neck cancer patients from different health settings across the world [PDF]
, 2019 Background: The aim was to collate and contrast patient concerns from a range of different head and neck cancer follow-up clinics around the world. Also, we sought to explore the relationship, if any, between responses to the patient concerns inventory ...
Alvear, Alvaro +36 more
core +2 more sources
Developmental Dynamics, EarlyView.Abstract Background Dentitions have diversified enormously during vertebrate evolution, involving reductions, modifications, or allocations to prey seizing and processing regions. A combination of ancient and novel features related to dental and oropharyngeal apparatuses is found in extant lineages of non‐teleost fishes, such as the gars.
Anna Pospisilova +4 more
wiley +1 more source
ApuA, a multifunctional x-glucan-degrading enzyme of Streptococcus suis, mediates adhesion to porcine epithelium and mucus [PDF]
, 2010 We have identified apuA in Streptococcus suis, which encodes a bifunctional amylopullulanase with conserved -amylase and pullulanase substrate-binding domains and catalytic motifs.
Ferrando, M.L. +4 more
core +2 more sources
Ictal semiology in fronto‐opercular epilepsy: A systematic review
Epileptic Disorders, EarlyView.Abstract A systematic review of the ictal semiology of fronto‐opercular seizures in focal epilepsy was carried out to assess possible anatomical‐clinical correlations and help guide interpretation of ictal semiology during pre‐surgical evaluation. PubMed and Embase databases were searched using the following keywords: “fronto‐opercular OR frontal ...
Zeynep Gokce‐Samar +9 more
wiley +1 more source
Quantifying the Pressure of Labial and Buccinator Regions Pre‐ and Post‐ Facial Nerve Reanimation
Head &Neck, EarlyView.ABSTRACT Background Flaccid facial nerve paralysis (FFNP) impairs oral function and quality of life. Tensor fascia lata slings (TFL) are used to improve oral competence. This study used the Iowa Oral Performance Instrument (IOPI) to measure oral competence in patients with FFNP undergoing facial reanimation.
Emma Charters +5 more
wiley +1 more source
Evaluation of human obstructive sleep apnea using computational fluid dynamics. [PDF]
, 2019 Obstructive sleep apnea (OSA) severity might be correlated to the flow characteristics of the upper airways. We aimed to investigate the severity of OSA based on 3D models constructed from CT scans coupled with computational fluid dynamics (CFD ...
Jafari, Behrouz +4 more
core
Head &Neck, EarlyView.ABSTRACT Background Current guidelines recommend surgical resection, definitive radiotherapy (RT), or concurrent chemoradiotherapy (CRT) for human papillomavirus (HPV)‐associated oropharyngeal squamous cell carcinoma (OPSCC). This study aimed to provide insight into practice patterns of providers who treat HPV‐associated OPSCC.
Sindhura Sridhar +2 more
wiley +1 more source