Results 11 to 20 of about 270,959 (189)

Study of humoral immunity indices for assessing physical exhaustion in sports

Медицинская иммунология, 2023
Studies of real opportunities for physical skills of athletes sufficiently depend on their adaptive potential for increasing physical loads. Extreme physical and psychoemotional loads may lead to overwork and decreased physical ability in professional ...
M. A. Myagkova, S. N. Petrochenko, Z. B. Bobrova, E. A. Orlova, A. S. Krylov, I. A. Moseikin   +5 more
doaj   +1 more source

The Orbit of the Orphan Stream [PDF]

, 2010
We use recent SEGUE spectroscopy and SDSS and SEGUE imaging data to measure the sky position, distance, and radial velocities of stars in the tidal debris stream that is commonly referred to as the "Orphan Stream." We fit orbital parameters to the data ...
Abazajian, Allende Prieto, An, Belokurov, Belokurov, Belokurov, Belokurov, Benjamin A. Willett, Brian Yanny, Chou, Clem, Combes, Geha, Grillmair, Heidi Jo Newberg, Helmi, Johnston, Jurić, Klypin, Klypin, Koposov, Koposov, Law, Lee, Lee, Majewski, Majewski, Majewski, Miyamoto, Munn, Murali, Newberg, Newberg, Odenkirchen, Schlegel, Teuben, Wilhelm, Willett, Willman, Xue, Yan Xu, Yanny, Yanny, Yanny, Yanny, Zucker   +45 more
core   +1 more source

Orphan anxiety [PDF]

Proceedings of the National Academy of Sciences, 1997
The recent discovery of several new endogenous opioid peptides has generated excitement over their potential physiological roles. For example, endomorphins are likely to have well defined functions due to their affinity and selectivity for a class of extensively studied opioid receptors (1).
J R, Walker, G F, Koob
openaire   +2 more sources

Pompe disease clinical and laboratory diagnostic features

Zdorovʹe Rebenka, 2017
Background. Analysis of Pompe disease (PD) clinical features in children in order to determine its main clinical and laboratory characteristics based on the results of laboratory and instrumental studies that allow to select such patients into the ...
N.O. Pichkur, N.V. Olkhovych, T.P. Ivanova, N.V. Samonenko   +3 more
doaj   +1 more source

FDA orphan products clinical trial grants: assessment of outcomes and impact on rare disease product development

Orphanet Journal of Rare Diseases, 2020
Background The Office of Orphan Products Development (OOPD) of the United States (U.S.) Food and Drug Administration (FDA) has awarded over 700 grants to conduct clinical trials of medicals products for rare diseases since 1983, leading to over 70 ...
Kathleen L. Miller, Christine Mueller, Gumei Liu, Katherine I. Miller Needleman, Janet Maynard   +4 more
doaj   +1 more source

Impact of orphan status on HIV treatment outcomes and retention in care of children and adolescents in Asia

Journal of Virus Eradication, 2016
An analysis of the impact of orphanhood at antiretroviral therapy (ART) initiation on HIV outcomes in Asia included 4300 children; 51% were male. At ART initiation, 1805 (42%) were non-orphans (median age: 3 years), 1437 (33%) were single orphans (6 ...
B.u.i.V.u. Huy, S.i.r.i.n.y.a. Teeraananchai, L.e.N.g.o.c. Oanh, J.o.h.n. Tucker, N.i.a. Kurniati, R.a.w.i.w.a.n. Hansudewechakul, K.h.a.n.h.H.u.u. Truong, V.o.h.i.t.h. Khol, L.a.m. Van Nguyen, V.i.e.t. Chau Do, P.a.g.a.k.r.o.n.g. Lumbiganon, N.a.n.t.a.k.a. Kongstan, T.o.r.s.a.k. Bunupuradah, T.a.v.i.t.i.y.a. Sudjaritruk, N.a.g.a.l.i.n.g.e.s.w.a.r.a.n. Kumarasamy, N.i.k.K.h.a.i.r.u.l.d.d.i.n.N.i.k. Yusoff, K.a.m.a.r.u.l.A.z.a.h.a.r. Mohd Razali, D.e.w.i.K.u.m.a.r.a. Wati, M.o.y.S.i.e.w. Fong, R.e.v.a.t.h.y. Nallusamy, A.z.a.r. Kariminia, A.n.n.e.t.t.e.H. Sohn   +21 more
doaj   +1 more source

Transport study of interleukin-1 inhibitors using a human in vitro model of the blood-brain barrier

Brain, Behavior, & Immunity - Health, 2021
The proinflammatory cytokine Interleukin-1 (IL-1), with its two isoforms α and β, has important roles in multiple pathogenic processes in the central nervous system.
Elisabet O. Sjöström, Maxime Culot, Lisa Leickt, Mikael Åstrand, Erik Nordling, Fabien Gosselet, Christina Kaiser   +6 more
doaj   +1 more source

Census of solo LuxR genes in prokaryotic genomes

Frontiers in Cellular and Infection Microbiology, 2015
luxR genes encode transcriptional regulators that control acyl homoserine lactone-based quorum sensing (AHL QS) in Gram negative bacteria. On the bacterial chromosome, luxR genes are usually found next or near to a luxI gene encoding the AHL signal ...
Sanjarbek eHudaiberdiev, Kumari Sonal eChoudhary, Roberto eVera Alvarez, Zsolt eGelencsér, Balázs eLigeti, Doriano eLamba, Sándor ePongor, Sándor ePongor   +7 more
doaj   +1 more source

Whole-genome analysis reveals the contribution of non-coding de novo transposon insertions to autism spectrum disorder

Mobile DNA, 2021
Background Retrotransposons have been implicated as causes of Mendelian disease, but their role in autism spectrum disorder (ASD) has not been systematically defined, because they are only called with adequate sensitivity from whole genome sequencing ...
Rebeca Borges-Monroy, Chong Chu, Caroline Dias, Jaejoon Choi, Soohyun Lee, Yue Gao, Taehwan Shin, Peter J. Park, Christopher A. Walsh, Eunjung Alice Lee   +9 more
doaj   +1 more source

Planktonic and sediment-associated aerobic methanotrophs in two seep systems along the North American margin [PDF]

, 2008
Methane vents are of significant geochemical and ecological importance. Notable progress has been made towards understanding anaerobic methane oxidation in marine sediments, however, the diversity and distribution of aerobic methanotrophs in the water ...
Orphan, Victoria J., Tavormina, Patricia L., Ussler, William, III   +2 more
core   +4 more sources