Results 221 to 230 of about 5,265,871 (311)

Narcolepsy and rapid eye movement sleep

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Since the first description of narcolepsy at the end of the 19th Century, great progress has been made. The disease is nowadays distinguished as narcolepsy type 1 and type 2. In the 1960s, the discovery of rapid eye movement sleep at sleep onset led to improved understanding of core sleep‐related disease symptoms of the disease (excessive ...
Francesco Biscarini, Lucie Barateau, Fabio Pizza, Giuseppe Plazzi, Yves Dauvilliers   +4 more
wiley   +1 more source

“Why can't they put us to sleep if we are suffering?”: La Nada and the desire for euthanasia among institutionalized older adults in Peru

Medical Anthropology Quarterly, EarlyView.
Abstract In this article, I examine how institutionalized older adults in Peru articulate suffering through the idiom of la nada—“nothingness”—and how this shapes desires for euthanasia. Moving from close ethnography of bodies in space and time to structural and ethical discourses on euthanasia, I argue that calls for euthanasia arise not only from ...
Magdalena Zegarra Chiappori
wiley   +1 more source

Estimating the minimal cost of delivering nutrition‐specific and nutrition‐sensitive interventions in Ethiopia

Maternal &Child Nutrition, EarlyView.
The minimum cost of the 10 years on identified nutrition‐specific and nutrition‐sensitive interventions of the National Food and Nutrition Strategy in Ethiopia is estimated to be US$ 2.55bn with an average annual cost of $250 million over 10 years (2021–2030), which is only 2.3% of the Ethiopian Annual GDP 111.27 billion US dollars in 2021 (World bank).
Yetayesh Maru, Firehiwot Mesfin, Arnaud Laillou, Ramadhani Noor, Shiva Raj Adhikari, Meseret Zelalem, Hiwot Darsene, Solomon Memire, Andarge Abie, Stanley Chitekwe   +9 more
wiley   +1 more source

The paediatric rheumatologist and orphan disease - a story without happy ending. [PDF]

Reumatologia, 2016
Roszkiewicz J, Biernacka-Zielińska M, Smolewska E.   +2 more
europepmc   +1 more source

Anaesthesia and orphan disease

European Journal of Anaesthesiology, 2019
Michael, Beer, Fritz, Fiedler
openaire   +3 more sources

Programmable Domestication: CRISPR, Pan‐Genomics and System Level Engineering for Next‐Generation Crops

Plant Biotechnology Journal, EarlyView.
Conceptual overview of programmable de novo domestication from genetic diversity discovery to crop deployment. The framework connects diverse germplasm and genomic resources with three trajectory pathways. Adaptive Rescue, Agronomic Refinement and Novel Chassis defined by biological distance, engineering complexity and breeding objectives.
Muhammad Mubashar Zafar, Hina Firdous, Ayesha Siddiqua, Ayesha Naveed, Abdul Razzaq, Sadam Munawar, Aqsa Ijaz, Zunaira Anwar, Sezai Ercisli, Xuefei Jiang, Qiao Fei   +10 more
wiley   +1 more source

A High‐Throughput Phenotyping Pipeline for Quinoa (Chenopodium quinoa) Panicles Using Image Analysis With Convolutional Neural Networks

Plant Breeding, EarlyView.
ABSTRACT Quinoa is a grain crop with excellent nutritional properties that has attracted global attention for its potential contribution to future food security in a changing climate. Despite its long history of cultivation, quinoa has been improved little by modern breeding and is a niche crop outside its native cultivation area.
Flavio Lozano‐Isla, Lydia Kienbaum, Bettina I. G. Haussmann, Karl Schmid   +3 more
wiley   +1 more source

Molecular Chaperone Networks in Plants: Maintaining Proteostasis and Enhancing Stress Resilience for Crop Improvement

Plant, Cell &Environment, EarlyView.
ABSTRACT Molecular chaperones play a central role in the plant proteostasis machinery by aiding the folding of nascent proteins, preventing aggregation, and repairing or degrading damaged proteins. These functions are especially essential during abiotic and biotic stress, which can destabilise cellular proteins and disrupt metabolic homoeostasis.
Mingfang Yang, Anqin Gao, Tsz‐Yan Chan, Hafiz Mamoon Rehman, Sehar Nawaz, Sehrish Bashir, Noman Mahmood, Muhammad Wajid Ullah, Chunlin Long, Hon‐Ming Lam, Muhammad Arif   +10 more
wiley   +1 more source

Aging Out of Place in Singapore: Effects of Fragmented Health and Long‐Term Care

Social Policy &Administration, EarlyView.
ABSTRACT This paper examines how healthcare fragmentation produces institutional displacement for Singapore's aging population, a phenomenon we conceptualise as ‘aging out of place’. It examines how older adults become systematically disconnected from care coordination while remaining physically in place.
M. Ramesh, Jiwei Qian
wiley   +1 more source

Translating gut microbiome research into therapies for type 1 diabetes

Experimental Physiology, EarlyView.
Abstract Type 1 diabetes (T1D) is characterised by the loss of functional pancreatic β‐cells, for which lifelong insulin therapy remains the standard of care. Given that the gut microbiome can influence host health and that shifts in gut microbial profiles have been observed in T1D, growing interest has emerged in the role of the gut microbiome in T1D,
Shanti P. Kok, Max Nieuwdorp, Elena Rampanelli   +2 more
wiley   +1 more source