Results 111 to 120 of about 43,399 (123)
ABSTRACT Hemoglobin S (HbS) polymerization inhibitor drugs such as voxelotor can result in a split peak in HbS as well as additional peaks with hemoglobin A in quantitative methods of HbS measurement. It is unclear how these results should be used to make transfusion decisions.
Sally Campbell‐Lee+5 more
wiley +1 more source
Beyond Conventional Approaches: The Revolutionary Role of Nanoparticles in Breast Cancer
This review explores integrated approach of nanotechnology to breast cancer diagnosis and treatment. We highlight imaging techniques for tumor detection and biomarker analysis in biological samples for early diagnosis. Advanced therapies, including targeted drug delivery and antibody‐drug conjugates, enable precise medication transport to cancer cells,
Mohan Liu+7 more
wiley +1 more source
Antioxidant Natural Plant Constituents for Diabetic Wound Repair
Antioxidant natural plant constituents promote diabetic wound repair by ameliorating oxidative stress, inhibiting inflammatory responses, and promoting tissue regeneration. ABSTRACT Diabetes mellitus is a prevalent metabolic disorder characterized by a prolonged hyperglycemic state, which can result in complications affecting multiple organ systems ...
Lele Meng+3 more
wiley +1 more source
ABSTRACT Background An African proverb, ‘It takes a village to raise a child’, is commonly acknowledged by the South African and other African populations. This proverb means that everybody is responsible for raising children into responsible human beings.
Livhuwani Precious Matshepete+2 more
wiley +1 more source
A Biosynthetic and Taxonomic Atlas of the Global Lichen Holobiont
This analysis of 794 publicly available lichen shotgun metagenomic datasets, covering 467 unique lichen species from 34 countries, revealed that lichens are complex holobionts. They harbour a variety of fungal, algal, and bacterial players with remarkable biosynthetic capabilities.
Samantha C. Waterworth+4 more
wiley +1 more source
Abstract Purpose To determine the relationship between the full‐field stimulus test (FST) and self‐reported visual function using the Michigan Retinal Degeneration Questionnaire (MRDQ) in patients with retinitis pigmentosa (RP). Methods In this cross‐sectional study, patients with clinically diagnosed RP (n = 31) performed FST to determine retinal ...
J. S. Karuntu+2 more
wiley +1 more source
Opportunities to Modulate Tumor Ecosystem Toward Successful Glioblastoma Immunotherapy
There remain outstanding gaps between the negative results from clinical trials and the actual potential of the immune system for glioblastoma. To bridge this crucial gap, we collaborated with Dr. Mariko Takahashi, an expert in immunobiology and drug development, and Dr. James J.
Mariko Takahashi+5 more
wiley +1 more source
ABSTRACT It is unclear whether Japanese top‐selling drugs have meaningful added therapeutic benefits to justify their high sales. This question is relevant as Japan's healthcare costs are rising consistently, particularly due to increasing drug prices.
Hayase Hakariya+5 more
wiley +1 more source
Current perspective on dental black stain of bacterial origin: A narrative review
Abstract Dental black stain is a form of external discoloration appearing as a dark line or an incomplete coalescence of dark spots in the cervical third of the tooth. This review aims to provide an up‐to‐date clinical and biological summary of dental black stain of bacterial origin.
Ahmed Al‐Shareef+5 more
wiley +1 more source
This study shows that the chemokine CXCL14 is induced by hepatotropic lytic virus in mice and humans and by inflammatory mediators such as IL‐6 and TNF. Hepatocytes are a source of CXCL14, which is released when cells die, making it an alarmin. CXCL14 knock‐out mice are partially protected from liver injury thanks to higher Ltreg recruitment.
Christelle Devisme+9 more
wiley +1 more source