Results 111 to 120 of about 43,399 (123)

Impact of Voxelotor on Red Blood Cell Exchange Therapeutic Procedures: Evaluation of Multi‐Institutional Procedure Data

open access: yesJournal of Clinical Apheresis, Volume 40, Issue 3, June 2025.
ABSTRACT Hemoglobin S (HbS) polymerization inhibitor drugs such as voxelotor can result in a split peak in HbS as well as additional peaks with hemoglobin A in quantitative methods of HbS measurement. It is unclear how these results should be used to make transfusion decisions.
Sally Campbell‐Lee   +5 more
wiley   +1 more source

Beyond Conventional Approaches: The Revolutionary Role of Nanoparticles in Breast Cancer

open access: yesMedComm – Biomaterials and Applications, Volume 4, Issue 2, June 2025.
This review explores integrated approach of nanotechnology to breast cancer diagnosis and treatment. We highlight imaging techniques for tumor detection and biomarker analysis in biological samples for early diagnosis. Advanced therapies, including targeted drug delivery and antibody‐drug conjugates, enable precise medication transport to cancer cells,
Mohan Liu   +7 more
wiley   +1 more source

Antioxidant Natural Plant Constituents for Diabetic Wound Repair

open access: yesMedComm – Biomaterials and Applications, Volume 4, Issue 2, June 2025.
Antioxidant natural plant constituents promote diabetic wound repair by ameliorating oxidative stress, inhibiting inflammatory responses, and promoting tissue regeneration. ABSTRACT Diabetes mellitus is a prevalent metabolic disorder characterized by a prolonged hyperglycemic state, which can result in complications affecting multiple organ systems ...
Lele Meng   +3 more
wiley   +1 more source

A Culturally Sensitive Psychosocial Support Programme for Orphans and Vulnerable Children in Vhembe District, South Africa

open access: yesPublic Health Challenges, Volume 4, Issue 2, June 2025.
ABSTRACT Background An African proverb, ‘It takes a village to raise a child’, is commonly acknowledged by the South African and other African populations. This proverb means that everybody is responsible for raising children into responsible human beings.
Livhuwani Precious Matshepete   +2 more
wiley   +1 more source

A Biosynthetic and Taxonomic Atlas of the Global Lichen Holobiont

open access: yesEnvironmental Microbiology, Volume 27, Issue 6, June 2025.
This analysis of 794 publicly available lichen shotgun metagenomic datasets, covering 467 unique lichen species from 34 countries, revealed that lichens are complex holobionts. They harbour a variety of fungal, algal, and bacterial players with remarkable biosynthetic capabilities.
Samantha C. Waterworth   +4 more
wiley   +1 more source

Relationship between the full‐field stimulus test and self‐reported visual function in patients with retinitis pigmentosa: REPEAT Study report No. 3

open access: yesActa Ophthalmologica, Volume 103, Issue 4, Page 396-403, June 2025.
Abstract Purpose To determine the relationship between the full‐field stimulus test (FST) and self‐reported visual function using the Michigan Retinal Degeneration Questionnaire (MRDQ) in patients with retinitis pigmentosa (RP). Methods In this cross‐sectional study, patients with clinically diagnosed RP (n = 31) performed FST to determine retinal ...
J. S. Karuntu   +2 more
wiley   +1 more source

Opportunities to Modulate Tumor Ecosystem Toward Successful Glioblastoma Immunotherapy

open access: yesCancer Science, Volume 116, Issue 6, Page 1482-1499, June 2025.
There remain outstanding gaps between the negative results from clinical trials and the actual potential of the immune system for glioblastoma. To bridge this crucial gap, we collaborated with Dr. Mariko Takahashi, an expert in immunobiology and drug development, and Dr. James J.
Mariko Takahashi   +5 more
wiley   +1 more source

Added Therapeutic Benefits of Top‐Selling Drugs in Japan: A Cross‐Sectional Study Using Health Technology Assessment

open access: yesClinical and Translational Science, Volume 18, Issue 6, June 2025.
ABSTRACT It is unclear whether Japanese top‐selling drugs have meaningful added therapeutic benefits to justify their high sales. This question is relevant as Japan's healthcare costs are rising consistently, particularly due to increasing drug prices.
Hayase Hakariya   +5 more
wiley   +1 more source

Current perspective on dental black stain of bacterial origin: A narrative review

open access: yesEuropean Journal of Oral Sciences, Volume 133, Issue 3, June 2025.
Abstract Dental black stain is a form of external discoloration appearing as a dark line or an incomplete coalescence of dark spots in the cervical third of the tooth. This review aims to provide an up‐to‐date clinical and biological summary of dental black stain of bacterial origin.
Ahmed Al‐Shareef   +5 more
wiley   +1 more source

CXCL14 Chemokine Exacerbates Acute Viral Hepatitis in Coronavirus MHV‐Infected Mice and Is Associated With Human Acute Viral Hepatitis

open access: yesThe FASEB Journal, Volume 39, Issue 10, 31 May 2025.
This study shows that the chemokine CXCL14 is induced by hepatotropic lytic virus in mice and humans and by inflammatory mediators such as IL‐6 and TNF. Hepatocytes are a source of CXCL14, which is released when cells die, making it an alarmin. CXCL14 knock‐out mice are partially protected from liver injury thanks to higher Ltreg recruitment.
Christelle Devisme   +9 more
wiley   +1 more source

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