Results 81 to 90 of about 22,199 (155)

Efficacy of anakinra in reducing progression to organ dysfunction in patients with pneumonia (INSPIRE): a randomised, double-blind, placebo-controlled, phase IIa trial. [PDF]

Lancet Reg Health Eur
Tavoulareas G, Kontakou-Zoniou O, Antonakos N, Tasouli E, Adamis G, Kakavoulis N, Michelakis E, Skopelitis I, Dakou K, Psarrakis C, Koufargyris P, Astriti M, Sympardi S, Giamarellos-Bourboulis EJ.   +13 more
europepmc   +1 more source

Nuclear receptors as therapeutic targets in metabolic and cardiovascular disorders. [PDF]

iScience
Li F, Chen Q, Dai Y, Lu L.
europepmc   +1 more source

Critical Evaluation of the Role of Transcription Factor RAR-Orphan Receptor-γt in the Development of Chronic Inflammatory Dermatological Diseases: A Promising Therapeutic Target. [PDF]

Biomolecules
Pramanik A, Mondal P, Bhattacharyya S.
europepmc   +1 more source

The emerging role of DNA methylation in the pathogenicity of bacterial pathogens. [PDF]

J Bacteriol
Ma Y-x, Wang X-d, Li X-m.
europepmc   +1 more source

A new hope for patients with Huntington's disease? [PDF]

EClinicalMedicine
eClinicalMedicine.
europepmc   +1 more source

OVERVIEW OF REGULATORY INITIATIVES IN THE EUROPEAN UNION TO STIMULATE RESEARCH AND ACCELERATE ACCESS TO ORPHAN DRUGS AND OTHER HIGH MEDICAL NEED PRODUCTS

Acta Poloniae Pharmaceutica - Drug Research, 2019
Aleksandra Baran-Kooiker, Marcin Czech, Coen Kooiker   +2 more
openaire   +1 more source

Role of interleukin 17 and T helper cells 17 cells as a new immune target and signalling in the pathogenesis and treatment of autoimmune thyroid diseases. [PDF]

Ann Med
He H, Jiang Y, Qiu J, Shen F, Qian D, Meng L.   +5 more
europepmc   +1 more source

Regulatory insights on adeno-associated virus-based gene therapies, cell- and tissue-based products, and CAR-T cell therapies: report from the 8th Asia Partnership Conference of Regenerative Medicine, April 24, 2025. [PDF]

Regen Ther
Tominaga S, Tsurumaki Y, Kagawa Y, Kito A, Miyano M, Ooka K, Kellathur SN, Hayashi S, Nomura M.   +8 more
europepmc   +1 more source

What Do Oral Drugs Really Look Like? Dose Regimen, Pharmacokinetics, and Safety of Recently Approved Small-Molecule Oral Drugs. [PDF]

J Med Chem
Brown DG.
europepmc   +1 more source

Societal participation in the development of orphan drugs: a systematic review. [PDF]

Front Med (Lausanne)
Akodad S, De Smedt D, Stevens H.
europepmc   +1 more source