Results 231 to 240 of about 101,906 (351)

Photoreceptor cells display a daily rhythm in the orphan receptor Esrrβ

, 2015
Stefanie Kunst, Tanja Wolloscheck, Markus Grether, Patricia Trunsch, Uwe Wolfrum, Rainer Spessert   +5 more
openalex  

Editor's evaluation: The orphan ligand, activin C, signals through activin receptor-like kinase 7

, 2022
Roger J. Davis
openalex   +1 more source

Modulation of KATP channels by diazoxide preserves mitochondrial function and barrier integrity under staurosporine‐induced epithelial stress

British Journal of Pharmacology, EarlyView.
Background and Purpose Intestinal barrier dysfunction caused by mitochondrial stress, oxidative damage and apoptosis, are hallmarks of dysbiosis‐associated gastrointestinal (GI) disorders. Staurosporine causes downstream features of dysbiosis‐induced epithelial damage.
Fatima Maqoud, Eleonora Malerba, Simona Drago, Antonella Orlando, Domenica Mallardi, Nicoletta De Lucia, Marina Antonacci, Annamaria Di Turi, Domenico Tricarico, Francesco Russo   +9 more
wiley   +1 more source

RAR-Related Orphan Receptor Gamma T (RoRγt)-Related Cytokines Play a Role in Neutrophil Infiltration of the Central Nervous System After Subarachnoid Hemorrhage

, 2019
Aminata P. Coulibaly, William Gartman, Valerie Swank, João Gomes, L. Ruozhuo, J. DeBacker, J. Javier Provencio   +6 more
openalex   +2 more sources

Thrombospondin‐4 is upregulated in abdominal aortic aneurysm: A vasoprotective response with potential therapeutic relevance

British Journal of Pharmacology, EarlyView.
TSP4 is upregulated in human and experimental AAA. TSP4 knockdown accelerated AAA formation and exacerbated both vascular inflammation and remodelling, emphasizing that TSP4 upregulation may represent a protective response against AAA. Our findings suggest that preserving TSP4 could be a useful strategy in the clinical management of AAA.
Laia Blanco‐Casoliva, Lidia Puertas‐Umbert, Judith Alonso, Rafael Almendra‐Pegueros, Saray Varona, Mercedes Camacho, Gemma Arderiu, Lluís Asmarats, Marta Alegret, Jose Martinez‐Gonzalez, Cristina Rodriguez   +10 more
wiley   +1 more source

Orphan receptor GPR153 facilitates vascular damage responses by modulating cAMP levels, YAP/TAZ signaling, and NF-κB activation. [PDF]

Nat Commun
Shao J, Kwon J, Wang T, Günther S, Tombor LS, Warwick T, Shaheryar Z, Brandes RP, Dimmeler S, Wenzel J, Offermanns S, Schwaninger M, Wettschureck N.   +12 more
europepmc   +1 more source

Orphanhood Status and Antecedents to Placement Among a Multinational Sample of Adults With Care Experience

Child &Family Social Work, EarlyView.
ABSTRACT Globally, millions of children are adopted or placed in alternative care settings (i.e., residential, foster, or kinship care). The current study explores the factors leading to separation from parents and adoption or placement in alternative care by investigating orphanhood status, perceived antecedents to placement, types of alternative care
Nicole Gilbertson Wilke, Jedd Medefind, Amanda Hiles Howard   +2 more
wiley   +1 more source

Novel Para-Phenylenediamine-Based Derivatives as Receptor Tyrosine Kinase-like Orphan Receptor 1 (ROR1) Inhibitors: An In Vitro Preliminary Characterization. [PDF]

ChemMedChem
Smaldone G, Miranda MR, Di Matteo F, Napolitano V, Aliberti M, Musella S, Di Sarno V, Lauro G, Bifulco G, Pepe G, Aquino G, Tecce MF, Gomez-Monterrey IM, Campiglia P, Ostacolo C, Bertamino A, Vestuto V, Ciaglia T.   +17 more
europepmc   +1 more source

Expectations and Concerns of Adoptive Families of Children With Fetal Alcohol Spectrum Disorder

Child &Family Social Work, EarlyView.
ABSTRACT Fetal alcohol spectrum disorder (FASD) is considered a condition that persists throughout life in people who have been exposed to alcohol during the gestation period. During the different stages of their lives, individuals with FASD face different challenges and adversities that—without the right resources and strategies—can contribute to ...
Dídac Gómez‐Santabrígida, Carme Montserrat, Marta Garcia‐Molsosa, Gala Lima‐López   +3 more
wiley   +1 more source

Orphan receptor-GPR52 inverse agonist efficacy in ameliorating chronic stress-related deficits in reward motivation and phasic accumbal dopamine activity in mice [PDF]

Transl Psychiatry
Pryce C, Zhang C, Kúkeľová D, Sigrist H, Hengerer B, Kratzer R, Mracek P, Omrani A, von Heimendahl M.   +8 more
europepmc   +2 more sources