Results 41 to 50 of about 2,987 (243)

Engineered Living Systems With Self‐Organizing Neural Networks: From Anatomy to Behavior and Gene Expression

Advanced Science, EarlyView.
Ectodermal tissue excised from Xenopus embryos self‐organizes into a three‐dimensional mucociliary organoid. Here, we generate a neural variant, termed neurobot, by implanting neural precursor cells. Neurobots develop mature neurons, adopt distinct morphologies, exhibit more complex motility, and respond differentially to neuroactive compounds. Imaging
Haleh Fotowat, Laurie O'Neill, Léo Pio‐Lopez, Megan M. Sperry, Patrick Erickson, Tiffany Lin, Michael Levin   +6 more
wiley   +1 more source

Introduction Of Moringa Leaves (Moringa Oleifera) Utilization As A High Nutritive Food Ingredient To Assist Nutrient Sufficiency For Children In Al Kaaf Orphanage Jabung, Malang

Journal of Innovation and Applied Technology, 2019
Daun kelor memiliki kandungan nutrisi yang cukup lengkap dan banyak sifat fungsional yang berguna untuk meningkatkan status gizi, khususnya bagi anak-anak.
Kiki Fibrianto, Wenny Bekti Sunarharum, Sudarminto Setyo Yuwono, Erni Sofia Murtini, Elok Waziiroh, Siti Narsito Wulan, Laila Yum Wahibah   +6 more
doaj   +1 more source

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

Advanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto, Tristan Dellazizzo Toth, Silvano Bond, Alexander Schmitz, Rim Diab, Sara Y. Ngo Tenlep, Brian Mooney, Silvia Erni, Martina Schobesberger, Olivier Scheidegger, Camille Peitsch, Smita Saxena   +11 more
wiley   +1 more source

Molluscum contagiosum and dental caries: A pertinent combination

Journal of Indian Society of Pedodontics and Preventive Dentistry, 2009
Background: In recent decades, there has been a tremendous surge of interest in issues related to child health. The present study was carried out to reveal the DMFT/deft status of children in the age group of 1-12 years, residing in orphanages from Pune,
Dixit S, Chaudhary M, Singh A
doaj  

Versatility in the design of orphanages: analysis of the history of European models

Архитектон
The article examines the problem of designing orphanages in the context of modern challenges such as military conflicts, economic crises and natural disasters in many countries of the world.
Akeel Aya
doaj   +1 more source

Spatiotemporal Organization of PTK7 Diffusion on Cell Surface Facilitates Tumor Invasion and Migration

Advanced Science, EarlyView.
The spatiotemporal dynamics of protein kinase diffusion govern cellular signaling and functions. Although vital for active receptors, the role of pseudokinase dynamics is unclear. Here, we use single‐molecule tracking to link faster diffusion of pseudokinase PTK7 to increased tumor cell invasion and migration.
Yaohua Li, Tao Pan, Yu Wang, Sainan Guo, Daiquan Chen, Liu Liu, Liwei Wang, Yang Sun, Weihong Tan   +8 more
wiley   +1 more source

SOCIAL FUND AND THE HIERARCHY OF MUHAMMADIYAH ORPHANAGES FINANCIAL INDEPENDENCY

Jurnal Ekonomi & Studi Pembangunan, 2019
This study aims to analyze the Muhammadiyah social fund and the hierarchy of financial independence of seven its orphanages in the Province of Daerah Istimewa Yogyakarta.
Yuli Utami, Azmi Najmimudin Azhari, Tjiptohadi Sawarjuwono, Abu Azam Alhadi   +3 more
doaj  

“Are you defective or immoral?”. Problems of selection and socialization of “morally defective” children in the 20s of the 20th century in Soviet Russia: regional aspects

Вестник Тамбовского университета. Серия: Гуманитарные науки, 2019
We consider the regional features of the social protection system of “morally handicapped” children in Tambov province in the first decade of Soviet government (1918–1928).
P. P. Shcherbinin, I. A. Shikunova
doaj   +1 more source

A Functionally Conserved Enhancer is Critical for PGC1A Expression and Thermogenesis in Brown Fat

Advanced Science, EarlyView.
An evolutionarily conserved enhancer controls PGC1A expression and thermogenic activation in brown adipose tissue. Integrative multi‐omics analyses identify two BAT‐specific enhancers, with PGC1A‐En1 functioning as the dominant regulatory element that maintains thermogenic capacity across species.
Duo Su, Haosen Yang, Xiaokai Li, Tingting Jiang, Siyuan Zhan, Tao Zhong, Jiazhong Guo, Yan Wang, Li Li, Hongping Zhang, Linjie Wang   +10 more
wiley   +1 more source

Universal Antibody‐Engineered Lipid Nanoparticles Potentiate Chemo‐Immunotherapy Against Triple‐Negative Breast Cancer by Reprogramming Tumor Cell Metabolism

Advanced Science, EarlyView.
A universal ROR1 antibody‐engineered lipid nanoparticle (LNP) is constructed by sequential drug encapsulation and antibody conjugation. The LNP not only enables enhanced chemotherapeutic efficiency by targeting drug delivery and precise localization of deep‐seated tumors through NIR‐II fluorescence imaging, but also remodels immunosuppressive TME ...
Yeneng Dai, Jiaqi Wang, Yu Liu, Guanda Jiao, Yuheng Gu, Yang Liu, Shengyu Fu, Xing Fan, Jialin Li, Ziang Guo, Kam Tong Leung, Lipeng Zhu, Qi Zhao   +12 more
wiley   +1 more source