Results 31 to 40 of about 154,634 (351)

Orphan drugs

open access: yesMedicinski pregled, 2013
Introduction. Drugs used for treatment of rare diseases are known worldwide under the term of orphan drugs because pharmaceutical companies have not been interested in ?adopting? them, that is in investing in research, developing and producing these drugs.
Svetlana Golocorbin-Kon   +4 more
openaire   +3 more sources

The extent of community and public support available to families caring for orphans in Malawi. [PDF]

open access: yes, 2009
There are an estimated 15 million AIDS orphans worldwide. Families play an important role in safeguarding orphans, but they may be increasingly compromised by the HIV/AIDS epidemic. The international aid community has recognized the need to help families
Heymann, S Jody, Kidman, Rachel
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The gulf between rhetoric & reality : an examination of the gap between development theory and development practice in the care of Cambodian orphans : a thesis presented in partial fulfilment of the requirements for the degree of Master of Philosophy in Development Studies at Massey University, Palmerston North Campus [PDF]

open access: yes, 2005
Like many other Developing World countries. Cambodia is in the midst of an orphan crisis. At least 77,000 children have lost their parents to AIDS and many thousands more have been orphaned by civil war. landmines and other tragedies.
Greenfield, Craig
core  

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Kenya research situation analysis on orphans and other vulnerable children [PDF]

open access: yes, 2009
This item is archived in the repository for materials published for the USAID supported Orphans and Vulnerable Children Comprehensive Action Research Project (OVC-CARE) at the Boston University Center for Global Health and Development.Addressing the ...
Beard, Jennifer   +6 more
core   +2 more sources

Hope Groups: a protocol for a cluster randomized controlled trial of psychosocial, mental health, and parenting support groups for Ukrainian caregivers during war and conflict

open access: yesTrials
Background In 2021, more than two-thirds of the world’s children lived in a conflict-affected country. In 2022, 13 million Ukrainians were forced to flee their homes after Russia’s full-scale invasion.
Sydney Tucker   +12 more
doaj   +1 more source

Modern Foreign Approaches to Open Adoption

open access: yesСовременная зарубежная психология
Context and relevance. The article presents a review of foreign literature on open and closed adoption, presents the results of studies that have not previously been translated into Russian, which explore various aspects of an adopted child's ...
Y.F. Chinareva
doaj   +1 more source

Nutritional status and dietary diversity of orphan and non – orphan children under five years: a comparative study in the Brong Ahafo region of Ghana

open access: yesBMC Nutrition, 2018
Background Undernutrition in children under 5 years is a major risk factor to child deaths and is related to impaired cognitive development and lower school performance.
Zakari Ali   +5 more
doaj   +1 more source

Saints and Orphans [PDF]

open access: yes, 2011
Postcard from Brooke Carstensen, during the Linfield College January Term Program in ...
Carstensen, Brooke
core   +1 more source

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