Results 61 to 70 of about 154,634 (351)
Advanced Science, EarlyView.Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
Helping the World\u27s Poor [PDF]
, 2007 What began as a health screening project for orphans ended with eye-opening lessons on the struggles facing some of the world’s most vulnerable ...
Mileham, Mardi
core +1 more source
Advanced Science, EarlyView.This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård +19 more
wiley +1 more source
World health dilemmas: Orphan and rare diseases, orphan drugs and orphan patients
World Journal of Methodology, 2014 According to global annual estimates hunger/malnutrition is the major cause of death (36 of 62 million). Cardiovascular diseases and cancer (5.44 of 13.43 million) are the major causes of death in developed countries, while lower respiratory tract infections, human immunodeficiency virus infection/acquired immunodeficiency syndrome, diarrhoeal disease,
Christina N, Kontoghiorghe +3 more
openaire +2 more sources
Advanced Science, EarlyView.The authors complement bovine pan‐SV with massive novel structural variations (SVs) identified through long‐read sequencing of 83 globally distributed cattle breeds. Repetitive sequence‐mediated SVs (rep‐SV) exhibit distinct dynamic patterns throughout cattle sub‐speciation and/or domestication processes, including uneven distribution between chr‐X and
Zhifan Guo +16 more
wiley +1 more source
Hope as the Mediator in the Relation Between Resilience and Life Satisfaction among Tibetan Orphans
SAGE OpenAs an extremely disadvantaged group, orphans have received extensive attention from researchers. However, previous research focused on their survival status and psychological distress.
Wei Yan +5 more
doaj +1 more source
Lessons from writing sessions: a school-based randomized trial with adolescent orphans in Rwanda [PDF]
European Journal of Psychotraumatology, 2014 Background: Treatments for adolescents affected by long-term loss in low- and middle-income countries are lacking. As school-based interventions are cost-efficient and easy to disseminate, an evaluation of this treatment setting for adolescents is ...
Johanna Unterhitzenberger, Rita Rosner
doaj +1 more source
HTA173 Time to Access Orphan Medicines in Greece [PDF]
, 2023 Anastasios Panagiotis Chantzaras +4 more
openalex +1 more source
Advanced Science, EarlyView.Upon inhalation, RM@TNT could persist long‐term in the diseased lungs, while undergoing disintegration to release TNT specifically within the ROS‐rich pathological microenvironments of SA‐ARDS. The released TNT was then precisely delivered to AMs via Tuftsin, where it released Nob intracellularly to activate BMAL1 expression, thus inhibiting AM ...
Yunlong Zhang +23 more
wiley +1 more source