Virtual cell construction for artificial intelligence‐driven drug discovery
Cells are the fundamental units through which genetic variation and pharmacological perturbations influence disease processes and therapeutic responses. However, cellular responses to intervention are strongly shaped by biological context, creating a central challenge for drug discovery: predicting how specific perturbations reshape cellular systems ...
Yuran Jia +5 more
wiley +1 more source
Climate refugia through the integration of topographic and biodiversity features offer a practical method to expand protection networks in central Chile. Our results show that the inclusion of relatively small climate refugia areas to protection networks can greatly improve ecosystem representation, advancing toward meeting Target 3 of the Kunming ...
Patricio Pliscoff +1 more
wiley +1 more source
Association of Fertility Preservation Benefit Mandates With Sperm Bank Network Adequacy: A Mixed-Methods Study. [PDF]
Berger JH +8 more
europepmc +1 more source
Pleural desmoid tumor mimicking a myofibroblastic neoplasm: Imaging-pathologic correlation. [PDF]
Villegas-Albo M +10 more
europepmc +1 more source
Incidental Detection With 18F-PSMA (Prostate-Specific Membrane Antigen)-1007 PET/CT of Multifocal Papillary Thyroid Carcinoma During Staging of Very High-Risk Prostate Adenocarcinoma: A Case Report. [PDF]
Bravo Quiroz JG +7 more
europepmc +1 more source
Genome-Resolved Functional Profiling of Osteoporosis-Associated Gut Bacteria Highlights Putative Metabolic and Immunogenic Signatures of the Gut-Bone Axis. [PDF]
Jiménez-Ortega RF +8 more
europepmc +1 more source
The Associations of Various Types of Hurricane-Related Exposures with Psychiatric and Substance Use Disorders in Puerto Rico Following Hurricane Maria. [PDF]
Lopez Mercado D +10 more
europepmc +1 more source

