Results 41 to 50 of about 1,617 (180)

Orthobiologic Injections Adjunctive to Cartilage‐Preserving Surgery May Improve Outcomes for Focal Knee Chondral Defects: A Systematic Review of Randomized Controlled Trials With Subgroup Meta‐analyses

Arthroscopy, EarlyView.
Purpose To perform a systematic review evaluating the efficacy of orthobiologic injections as adjuncts to cartilage‐preserving surgery in improving clinical, radiographic, and histologic outcomes in adults with focal knee cartilage defects. Methods Four databases (PubMed, MEDLINE, EMBASE, and Scopus) were searched through September 2025 for randomized ...
Benjamin Blackman, Alexandru Pulbere, Seth Ybema, Marc Daniel Bouchard, Prushoth Vivekanantha, Praveen Sritharan, Darren de SA, Olufemi R. Ayeni, Jeffrey Kay   +8 more
wiley   +1 more source

Orthobiologics in the treatment of hip disorders

World Journal of Stem Cells, 2021
Orthobiologics are biological materials that are intended for the regeneration or healing of bone, cartilage and soft tissues. In this review we discuss the use of orthobiologics for hip disorders providing an update. The orthobiologics included in this article are hyaluronic acid, platelet rich plasma, bone marrow, adipose tissue and expanded ...
Kruel, André Vinícius Saueressig, Ribeiro, Lucas Leite, Gusmão, Paulo David, Huber, Stephany Cares, Lana, José Fábio Santos Duarte   +4 more
openaire   +2 more sources

Effectiveness of Platelet-Rich Plasma and Bone Marrow Aspirate Concentrate as Treatments for Chronic Hindlimb Proximal Suspensory Desmopathy

Frontiers in Veterinary Science, 2021
This retrospective study aimed to evaluate the clinical effect of bone marrow aspirate concentrate (BMAC) and leukocyte rich PRP (LR-PRP) compared to horses undergoing controlled exercise alone in horses with >3 months proximal suspensory desmopathy ...
Grigorios Maleas, Mahmoud Mageed
doaj   +1 more source

Long-Term Durability of Bilateral Two-Level Stellate Ganglion Blocks in Posttraumatic Stress Disorder: A Six-Month Retrospective Analysis

Clinical and Translational Neuroscience
Posttraumatic stress disorder (PTSD) is a common neuropsychiatric condition with a complex etiology. Stellate Ganglion Block (SGB) is a novel but well-observed procedure for treating the disorder.
Sean W. Mulvaney, Sanjay Mahadevan, Kyle J. Dineen, Roosevelt Desronvilles, Kristine L. Rae Olmsted   +4 more
doaj   +1 more source

Current Status of PRP Manufacturing Requirements & European Regulatory Frameworks: Practical Tools for the Appropriate Implementation of PRP Therapies in Musculoskeletal Regenerative Medicine

Bioengineering, 2023
Providing accurate and up-to-date practical tools enabling oversight of platelet-rich plasma (PRP) legislation and of the appropriate standards to be implemented for its manufacture and use in Europe is a demanding task.
Patrick Sebbagh, Alessandro Cannone, Gerald Gremion, Vincent Gremeaux, Wassim Raffoul, Nathalie Hirt-Burri, Murielle Michetti, Philippe Abdel-Sayed, Alexis Laurent, Nathalie Wardé, Lee Ann Applegate   +10 more
doaj   +1 more source

sj-pdf-1-jba-10.1177_08853282211059294 – Supplemental Material for Evolution of silicate bioglass particles as porous microspheres with a view towards orthobiologics

, 2022
Supplemental Material, sj-pdf-1-jba-10.1177_08853282211059294 for Evolution of silicate bioglass particles as porous microspheres with a view towards orthobiologics by Md Towhidul Islam, Nur Aisyah Nuzulia, Laura Macri-Pellizzeri, Farah Nigar, Yessie W ...
Nur Aisyah Nuzulia (11988466), Laura Macri-Pellizzeri (6593123), Yessie W. Sari (11501255), Md Towhidul Islam (11988463), Farah Nigar (11988469), Ifty Ahmed (1821562)   +5 more
core   +1 more source

Three-Month Durability of Bilateral Two-Level Stellate Ganglion Blocks in Patients with Generalized Anxiety Disorder: A Retrospective Analysis

Brain Sciences
Purpose: Determine if performing ultrasound-guided, bilateral, two-level cervical sympathetic chain blocks (2LCSB) (performed on subsequent days) provides durable improvement in symptoms associated with anxiety.
Sean W. Mulvaney, Kyle J. Dineen, Sanjay Mahadevan, Roosevelt Desronvilles, Kristine L. Rae Olmsted   +4 more
doaj   +1 more source

Raman Fingerprint of Extracellular Vesicles and Conditioned Media for the Reproducibility Assessment of Cell-Free Therapeutics

Frontiers in Bioengineering and Biotechnology, 2021
Extracellular Vesicles (EVs) and Conditioned Medium (CM) are promising cell-free approaches to repair damaged and diseased tissues for regenerative rehabilitation purposes.
Cristiano Carlomagno, Chiara Giannasi, Chiara Giannasi, Stefania Niada, Marzia Bedoni, Alice Gualerzi, Anna Teresa Brini, Anna Teresa Brini   +7 more
doaj   +1 more source

Autologous minimally manipulated adipose‐derived stromal vascular fraction in knee osteoarthritis: Lasting symptom relief and imaging evidence from a 12‐month prospective study

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To evaluate the safety and efficacy of intra‐articular autologous transplantation of adipose‐derived connective tissue micrografts rich in stromal vascular fraction (CTM‐SVF), obtained using an enzyme‐free system (Hy‐Tissue® SVF) for knee osteoarthritis (OA). Methods Thirty patients (mean age of 53.3 ± 6.4 years) with Kellgren–Lawrence
Laura Mangiavini, Nicolò Rossi, Riccardo Giorgino, Francesco Borelli, Alessandra Colombini, Paola De Luca, Simona Landoni, Luca Maria Sconfienza, Carmelo Messina, Irene Beriotto, Giuseppe M. Peretti, Laura de Girolamo   +11 more
wiley   +1 more source

Platelet Rich Plasma and Platelet-Related Products in the Treatment of Radiculopathy—A Systematic Review of the Literature

Biomedicines, 2022
Back pain with radicular symptoms is associated with detrimental physical and emotional functioning and economic burden. Conservative treatments including physical, pharmacologic and injection therapy may not provide clinically significant or long ...
Eva Kubrova, Gabriel A. Martinez Alvarez, Yeng F. Her, Robert Pagan-Rosado, Wenchun Qu, Ryan S. D’Souza   +5 more
doaj   +1 more source