Results 51 to 60 of about 1,617 (180)

Safety profile comparison of intra‐articular corticosteroids, hyaluronic acid, platelet‐rich plasma, and cell‐based injections for knee osteoarthritis: A systematic review and meta‐analysis by the ESSKA Orthobiologics Initiative

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose The aim was to compare the safety profiles of corticosteroids (CS), hyaluronic acid (HA), blood‐derived products based on platelet concentrates (for simplicity indicated as PRP ‐ platelet‐rich plasma ‐ being PRP the most common product), and cell‐based therapies (namely products exploiting the therapeutic function of mesenchymal ...
Alessandro Bensa, Andrea Piano, Giacomo Arthur Fumagalli, Laura de Girolamo, Lior Laver, Jérémy Magalon, Mikel Sánchez, Thomas Tischer, Giuseppe Filardo   +8 more
wiley   +1 more source

Efficacy and Duration of Intra-Articular Autologous Micro-Fragmented Adipose Tissue in Athletes with Ankle Osteoarthritis: A 36-Month Follow-Up Study

Applied Sciences, 2023
Introduction: The intra-articular injection of autologous micro-fragmented adipose tissue (MAT) is increasingly used to manage pain and dysfunction in subjects with osteoarthritis (OA). The purpose of this retrospective study was to report the safety and
Venanzio Iacono, Simone Natali, Luca De Berardinis, Daniele Screpis, Antonio Pompilio Gigante, Claudio Zorzi   +5 more
doaj   +1 more source

Managing the meniscus part I—Anatomy, biomechanics, and treatment strategies for the atraumatic meniscus tear

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose The purpose of this article is to serve as the first of a two‐part review on the meniscus; in this review, we will establish the background on anatomy and pathogenesis of the meniscus, as well as the effect of the meniscus on native knee kinematics and function.
Ehab M. Nazzal, Jonathan D. Hughes, Armin Runer, Matthew P. Kolevar, Jorge Chahla, Robert G. Marx, James J. Irrgang, Roman Seil, Berte Bøe, David Parker, Ryosuke Kuroda, Eric H. Senorski, Sachin Tapasvi, Volker Musahl   +13 more
wiley   +1 more source

Return to sport after meniscectomy, meniscal repair, and meniscal allograft transplantation for meniscal lesions in athletes: A systematic review and meta‐analysis

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose The aim of this systematic review and meta‐analysis was to quantify and compare the evidence on the results obtained with the surgical treatments for meniscal lesions in athletes. Methods A literature search was conducted on PubMed, Cochrane and Web of Science in August 2025 according to the PRISMA guidelines.
Alessandro Bensa, Andrea Piano, Giacomo Arthur Fumagalli, Aaron John Krych, Peter Verdonk, Giuseppe Filardo   +5 more
wiley   +1 more source

sj-pdf-1-ajs-10.1177_03635465211031275 – Supplemental material for Colony Forming Potential and Protein Composition of Commercial Umbilical Cord Allograft Products in Comparison With Autologous Orthobiologics

, 2021
Supplemental material, sj-pdf-1-ajs-10.1177_03635465211031275 for Colony Forming Potential and Protein Composition of Commercial Umbilical Cord Allograft Products in Comparison With Autologous Orthobiologics by Dustin R. Berger, Christopher J.
Neven J. Steinmetz (11284987), John D. Kisiday (2260714), Dustin R. Berger (11284981), Christopher J. Centeno (11284984), C. Wayne McIlwraith (5705075)   +4 more
core   +1 more source

Autologous adipose‐derived mesenchymal stromal cell injection for knee osteoarthritis improves pain and function without a clear increase in adverse events: A systematic review and meta‐analysis of randomized controlled trials

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To systematically review randomized controlled trials and quantitatively evaluate the efficacy and safety of injections of autologous adipose‐derived mesenchymal stromal cells (AD‐MSCs) in patients with knee osteoarthritis (OA). Methods Multiple electronic databases were searched with no date restrictions for randomized controlled ...
Joo Hyung Han, Min Jung, Kwangho Chung, Hyun‐Soo Moon, Se‐Han Jung, Seung Hoon Baik, Jeongmo Koo, Woongseob Sim, Sung‐Hwan Kim   +8 more
wiley   +1 more source

Updates on intra‐articular corticosteroid administration in horses

Equine Veterinary Education, EarlyView.
Summary Intra‐articular (IA) corticosteroid administration in equine athletes has gained increased attention recently, particularly in racing. Despite widespread corticosteroid use in equine practice for decades, there are still a lack of equine‐specific studies to address key questions related to their use.
K. Tanner, L. Bass, C. Kawcak, L. V. Schnabel, K. L. Hallowell, L. M. Pezzanite   +5 more
wiley   +1 more source

Short‐term welfare assessment of a single ultrasound‐guided adipose tissue aspiration in standing sedated horses

Equine Veterinary Education, EarlyView.
Summary Background Adipose tissue‐derived mesenchymal stem cells (AT‐MSCs) are entering the market of orthobiologics suitable for managing musculoskeletal disorders in horses, due to their accessibility and reparative capacity. Ethical considerations in developing allogeneic products require a low‐morbidity approach to tissue harvest.
A. Nedergaard, K. M. Kalka, C. Lindegaard   +2 more
wiley   +1 more source

Core decompression augmented with bone marrow aspirate concentrate for refractory distal sesamoid bone pathology in horses: A retrospective clinical study

Veterinary Surgery, EarlyView.
Abstract Objective To determine short‐ and long‐term outcomes of core decompression combined with autologous bone marrow aspirate concentrate (BMAC) in treating moderate‐to‐severe refractory distal sesamoid bone (DSB) trabecular pathology in horses. Study design Retrospective observational study. Animals A total of 21 client‐owned Warmblood horses with
Grigorios Maleas, Mahmoud Mageed, Kristyna Hargitaiova   +2 more
wiley   +1 more source

A personalized osteoarthritic joint-on-a-chip as a screening platform for biological treatments

Materials Today Bio
Osteoarthritis (OA) is a highly disabling pathology, characterized by synovial inflammation and cartilage degeneration. Orthobiologics have shown promising results in OA treatment thanks to their ability to influence articular cells and modulate the ...
Dalila Petta, Daniele D'Arrigo, Shima Salehi, Giuseppe Talò, Lorenzo Bonetti, Marco Vanoni, Luca Deabate, Luigi De Nardo, Gabriele Dubini, Christian Candrian, Matteo Moretti, Silvia Lopa, Chiara Arrigoni   +12 more
doaj   +1 more source