Results 21 to 30 of about 9,735 (200)
Fatal Encephalitis Caused by Cristoli Virus, an Emerging Orthobunyavirus, France [PDF]
Emerging Infectious Diseases, 2020 We report the discovery of a new orthobunyavirus, Cristoli virus, by means of shotgun metagenomics. The virus was identified in an immunodepressed patient with fatal encephalitis.
Christophe Rodriguez +10 more
doaj +4 more sources
Lineage-matched Oropouche virus mRNA-LNP vaccines confer complete, cross-protective immunity in mice [PDF]
mBioOropouche virus (OROV) is an emerging orthobunyavirus responsible for recurrent and increasingly widespread outbreaks across South and Central America, including a recent epidemic that elevated global concern.
Yumiko Yamada +11 more
doaj +2 more sources
Evidence of Oropouche Orthobunyavirus Infection, Colombia, 2017 [PDF]
Emerging Infectious Diseases, 2021 We describe an Oropouche orthobunyavirus infection in a women 28 years of age in Colombia. We confirmed the diagnosis by viral isolation, quantitative reverse transcription PCR, and phylogenetic analysis of the small, medium, and large genomic segments. The virus is related to a strain isolated in Ecuador in 2016.
Doris E. Gómez-Camargo +8 more
openaire +3 more sources
Severe Sepsis Caused by California Serogroup Orthobunyavirus [PDF]
Emerging Infectious Diseases, 2015 To the Editor: The California serogroup (CAL) of orthobunyaviruses, including Jamestown Canyon virus (JCV) and La Crosse virus (LACV), can cause neuroinvasive disease in humans (1–3). The epidemiology and clinical spectrum of LACV are well described (3), whereas less is known about JCV. JCV is distributed throughout temperate North America, and its
Daniel K. Rogstad +3 more
doaj +2 more sources
The Native Orthobunyavirus Ribonucleoprotein Possesses a Helical Architecture [PDF]
mBio, 2022 Bunyaviruses are emerging RNA viruses that cause significant disease and economic burden and for which vaccines or therapies approved for humans are not available. The bunyavirus genome is wrapped up by the nucleoprotein (NP) and interacts with the viral polymerase, forming a ribonucleoprotein (RNP).
Francis R. Hopkins +7 more
openaire +4 more sources
Genome encapsidation by orthobunyavirus nucleoproteins [PDF]
Proceedings of the National Academy of Sciences, 2013 All negative-sense, single-stranded RNA (−ssRNA) viruses encode a nucleoprotein (NP), the major function of which is to bind viral RNAs and encapsidate them as ribonucleoprotein complexes (RNPs) (1, 2). Consequently, the genomes of −ssRNA viruses do not exist as naked RNA but rather as protein–RNA complexes with high-order structures. In PNAS, Li et al.
Wenjie, Zheng, Yizhi Jane, Tao
openaire +2 more sources
Human Orthobunyavirus Infections, Tefé, Amazonas, Brazil [PDF]
PLoS Currents, 2018 Several orthobunyaviruses are important arthropod-borne pathogens, responsible for a variety of diseases in humans, from acute febrile illness to encephalitis.We collected serum samples from a series of dengue suspected cases in Tefé, a mid-size city located in the interior of the Amazonas state, Brazil.
Naveca, Felipe Gomes +3 more
openaire +2 more sources
Ťahyňa virus—A widespread, but neglected mosquito‐borne virus in Europe
Zoonoses and Public Health, Volume 70, Issue 5, Page 371-382, August 2023., 2023 Abstract Ťahyňa virus (TAHV) is an orthobunyavirus and was the first arbovirus isolated from mosquitoes in Europe and is associated with floodplain areas as a characteristic biotope, hares as reservoir hosts and the mammal‐feeding mosquitoes Aedes vexans as the main vector.
Kristína Mravcová +6 more
wiley +1 more source
Crystal structure of Schmallenberg orthobunyavirus nucleoprotein-RNA complex reveals a novel RNA sequestration mechanism [PDF]
, 2013 Schmallenberg virus (SBV) is a newly emerged orthobunyavirus (family Bunyaviridae) that has caused severe disease in the offspring of farm animals across Europe.
Bottcher, B. +4 more
core +1 more source