Results 21 to 30 of about 2,574 (186)

In vitro and in vivo studies of the Interferon-alpha action on distinct Orthobunyavirus

open access: greenAntiviral Research, 2007
Oropouche, Caraparu, Guama, Guaroa and Tacaiuma viruses (Orthobunyavirus genus) cause human febrile illnesses and/or encephalitis. To achieve a therapeutical agent to prevent and/or treat these diseases we evaluated the antiviral action of Interferon-alpha (IFN-alpha) on these orthobunyaviruses.
Márcia Cristina Livonesi   +3 more
openalex   +5 more sources

Mammals Preferred: Reassortment of Batai and Bunyamwera orthobunyavirus Occurs in Mammalian but Not Insect Cells

open access: yesViruses, 2021
Reassortment is a viral genome-segment recomposition known for many viruses, including the orthobunyaviruses. The co-infection of a host cell with two viruses of the same serogroup, such as the Bunyamwera orthobunyavirus and the Batai orthobunyavirus ...
Anna Heitmann   +9 more
doaj   +1 more source

Evidence of Oropouche Orthobunyavirus Infection, Colombia, 2017 [PDF]

open access: yesEmerging Infectious Diseases, 2021
We describe an Oropouche orthobunyavirus infection in a women 28 years of age in Colombia. We confirmed the diagnosis by viral isolation, quantitative reverse transcription PCR, and phylogenetic analysis of the small, medium, and large genomic segments. The virus is related to a strain isolated in Ecuador in 2016.
Eugenio J Abente   +8 more
openaire   +4 more sources

dsRNA-ended genomes in orthobunyavirus particles and infected cells

open access: bronzeVirology, 2016
dsRNA-ended genome RNPs accumulate during LaCrosse bunyavirus infection. The possible significance of these dsRNA structures for orthobunyavirus replication and survival are discussed.
Daniel Kolakofsky
openalex   +4 more sources

Ťahyňa virus—A widespread, but neglected mosquito‐borne virus in Europe

open access: yesZoonoses and Public Health, Volume 70, Issue 5, Page 371-382, August 2023., 2023
Abstract Ťahyňa virus (TAHV) is an orthobunyavirus and was the first arbovirus isolated from mosquitoes in Europe and is associated with floodplain areas as a characteristic biotope, hares as reservoir hosts and the mammal‐feeding mosquitoes Aedes vexans as the main vector.
Kristína Mravcová   +6 more
wiley   +1 more source

Genome encapsidation by orthobunyavirus nucleoproteins [PDF]

open access: yesProceedings of the National Academy of Sciences, 2013
All negative-sense, single-stranded RNA (−ssRNA) viruses encode a nucleoprotein (NP), the major function of which is to bind viral RNAs and encapsidate them as ribonucleoprotein complexes (RNPs) (1, 2). Consequently, the genomes of −ssRNA viruses do not exist as naked RNA but rather as protein–RNA complexes with high-order structures. In PNAS, Li et al.
Wenjie Zheng, Yizhi Jane Tao
openaire   +2 more sources

Novel murine models for studying Cache Valley virus pathogenesis and in utero transmission

open access: yesEmerging Microbes and Infections, 2021
Cache Valley virus (CVV) is a prevalent emerging pathogen of significant importance to agricultural and human health in North America. Emergence in livestock can result in substantial agroeconomic losses resulting from the severe embryonic lethality ...
Krisangel López   +11 more
doaj   +1 more source

The seminal plasma microbiome of men with testicular germ cell tumours described by small RNA sequencing

open access: yesAndrology, Volume 11, Issue 4, Page 756-769, May 2023., 2023
Abstract Background It has been estimated that microorganisms are involved in the pathogenesis of approximately 20% of all cancers. Testicular germ cell tumours (TGCTs) are the most common type of malignancy in young men and arise from the precursor cell, germ cell neoplasia in situ (GCNIS).
Nina Mørup   +5 more
wiley   +1 more source

Prioritisation of zoonotic diseases for coordinated surveillance systems under the One Health approach for cross‐border pathogens that threaten the Union

open access: yesEFSA Journal, Volume 21, Issue 3, March 2023., 2023
Abstract In the context of the initiative ‘CP‐g‐22‐04.01 Direct grants to Member States’ authorities', EFSA was requested to develop and conduct a prioritisation of zoonotic diseases, in collaboration with Member States, to identify priorities for the establishment of a coordinated surveillance system under the One Health approach.
European Food Safety Authority (EFSA)   +7 more
wiley   +1 more source

Epidemiology of Shuni Virus in Horses in South Africa

open access: yesViruses, 2021
The Orthobunyavirus genus, family Peribunyaviridae, contains several important emerging and re-emerging arboviruses of veterinary and medical importance.
Thopisang P. Motlou   +2 more
doaj   +1 more source

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