Results 21 to 30 of about 2,574 (186)
In vitro and in vivo studies of the Interferon-alpha action on distinct Orthobunyavirus
Oropouche, Caraparu, Guama, Guaroa and Tacaiuma viruses (Orthobunyavirus genus) cause human febrile illnesses and/or encephalitis. To achieve a therapeutical agent to prevent and/or treat these diseases we evaluated the antiviral action of Interferon-alpha (IFN-alpha) on these orthobunyaviruses.
Márcia Cristina Livonesi+3 more
openalex +5 more sources
Reassortment is a viral genome-segment recomposition known for many viruses, including the orthobunyaviruses. The co-infection of a host cell with two viruses of the same serogroup, such as the Bunyamwera orthobunyavirus and the Batai orthobunyavirus ...
Anna Heitmann+9 more
doaj +1 more source
Evidence of Oropouche Orthobunyavirus Infection, Colombia, 2017 [PDF]
We describe an Oropouche orthobunyavirus infection in a women 28 years of age in Colombia. We confirmed the diagnosis by viral isolation, quantitative reverse transcription PCR, and phylogenetic analysis of the small, medium, and large genomic segments. The virus is related to a strain isolated in Ecuador in 2016.
Eugenio J Abente+8 more
openaire +4 more sources
dsRNA-ended genomes in orthobunyavirus particles and infected cells
dsRNA-ended genome RNPs accumulate during LaCrosse bunyavirus infection. The possible significance of these dsRNA structures for orthobunyavirus replication and survival are discussed.
Daniel Kolakofsky
openalex +4 more sources
Ťahyňa virus—A widespread, but neglected mosquito‐borne virus in Europe
Abstract Ťahyňa virus (TAHV) is an orthobunyavirus and was the first arbovirus isolated from mosquitoes in Europe and is associated with floodplain areas as a characteristic biotope, hares as reservoir hosts and the mammal‐feeding mosquitoes Aedes vexans as the main vector.
Kristína Mravcová+6 more
wiley +1 more source
Genome encapsidation by orthobunyavirus nucleoproteins [PDF]
All negative-sense, single-stranded RNA (−ssRNA) viruses encode a nucleoprotein (NP), the major function of which is to bind viral RNAs and encapsidate them as ribonucleoprotein complexes (RNPs) (1, 2). Consequently, the genomes of −ssRNA viruses do not exist as naked RNA but rather as protein–RNA complexes with high-order structures. In PNAS, Li et al.
Wenjie Zheng, Yizhi Jane Tao
openaire +2 more sources
Novel murine models for studying Cache Valley virus pathogenesis and in utero transmission
Cache Valley virus (CVV) is a prevalent emerging pathogen of significant importance to agricultural and human health in North America. Emergence in livestock can result in substantial agroeconomic losses resulting from the severe embryonic lethality ...
Krisangel López+11 more
doaj +1 more source
Abstract Background It has been estimated that microorganisms are involved in the pathogenesis of approximately 20% of all cancers. Testicular germ cell tumours (TGCTs) are the most common type of malignancy in young men and arise from the precursor cell, germ cell neoplasia in situ (GCNIS).
Nina Mørup+5 more
wiley +1 more source
Abstract In the context of the initiative ‘CP‐g‐22‐04.01 Direct grants to Member States’ authorities', EFSA was requested to develop and conduct a prioritisation of zoonotic diseases, in collaboration with Member States, to identify priorities for the establishment of a coordinated surveillance system under the One Health approach.
European Food Safety Authority (EFSA)+7 more
wiley +1 more source
Epidemiology of Shuni Virus in Horses in South Africa
The Orthobunyavirus genus, family Peribunyaviridae, contains several important emerging and re-emerging arboviruses of veterinary and medical importance.
Thopisang P. Motlou+2 more
doaj +1 more source