Results 81 to 90 of about 22,113 (299)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Constructing orthogonal wavelet bases on the sphere [PDF]

open access: yes, 2008
The stereographic projection determines a bijection between the two-sphere, minus the North Pole, and the tangent plane at the South Pole. This correspondence induces a unitary map between the corresponding $L^2$ spaces.
16th European Signal Processing Conference (EUSIPCO 2008)   +2 more
core  

Face Recognition and Gender Classification Using Orthogonal Nearest Neighbour Feature Line Embedding

open access: yesInternational Journal of Advanced Robotic Systems, 2012
In this paper, a novel manifold learning algorithm for face recognition and gender classification – orthogonal nearest neighbour feature line embedding (ONNFLE) – is proposed.
Gang-Feng Ho   +3 more
doaj   +1 more source

Sums of A Pair of Orthogonal Frames

open access: yesMathematics, 2019
Frames are more stable as compared to bases under the action of a bounded linear operator. Sums of different frames under the action of a bounded linear operator are studied with the help of analysis, synthesis and frame operators.
Ghanshyam Bhatt
doaj   +1 more source

Orthogonal Chirp-Based Ultrasonic Positioning [PDF]

open access: yesSensors, 2017
This paper presents a chirp based ultrasonic positioning system (UPS) using orthogonal chirp waveforms. In the proposed method, multiple transmitters can simultaneously transmit chirp signals, as a result, it can efficiently utilize the entire available frequency spectrum.
Mohammad Omar Khyam   +3 more
openaire   +4 more sources

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

A Hybrid Orthogonal Polynomial Approach for Optimal Control of Fractional Parabolic PDEs: Combining Legendre, Chebyshev, and Jacobi Polynomials [PDF]

open access: yesControl and Optimization in Applied Mathematics
This paper presents a novel hybrid orthogonal polynomial method for solving optimal control problems governed by fractional parabolic PDEs. By strategically weighting and combining these polynomial bases, the method adaptively leverages their respective ...
Muhammed Hassanein Al-Hakeem   +2 more
doaj   +1 more source

Kernel-based learning of orthogonal functions

open access: yesNeurocomputing, 2020
Estimating a set of orthogonal functions from a finite set of noisy data plays a crucial role in several areas such as imaging, dictionary learning and compressed sensing. The problem turns out especially hard due to its intrinsic non-convexity. In this paper, we solve it by recasting it in the framework of multi-task learning in Hilbert spaces, where ...
Scampicchio, G. Pillonetto, M. Bisiacco
openaire   +4 more sources

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

On computing least order fault detectors using rational nullspace bases [PDF]

open access: yes, 2003
We propose a numerically reliable computational approach to design least order fault detectors using descriptor system techniques. This approach is based on a new numerically stable algorithm to compute least order rational nullspace bases of rational ...
A. Varga, Varga, Andras
core   +1 more source

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